Subacute sclerosing panencephalitis (SSPE) is a late-onset and fatal viral disease caused by persistent infection of the central nervous system by measles virus (MeV). We present the case of a 10-year-old child from South Asia affected by SSPE, stabilized with a combination of intrathecal interferon-α2b (INF-α2b) injections and oral inosiplex and how we continued the treatment when inosiplex was commercially stopped worldwide.
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http://dx.doi.org/10.1080/22221751.2022.2148563 | DOI Listing |
Front Hum Neurosci
December 2024
Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands.
Introduction: As brain-computer interfacing (BCI) systems transition fromassistive technology to more diverse applications, their speed, reliability, and user experience become increasingly important. Dynamic stopping methods enhance BCI system speed by deciding at any moment whether to output a result or wait for more information. Such approach leverages trial variance, allowing good trials to be detected earlier, thereby speeding up the process without significantly compromising accuracy.
View Article and Find Full Text PDFFocus (Am Psychiatr Publ)
January 2025
Department of Management, University of Utah, Salt Lake City.
Stigma has been a pervasive and stubborn part of the mental illness landscape, but it need not be. This article explores the nature of mental health stigma, where it comes from, how it is manifested, how it harms people, and what can be done about it. The article articulates the need to clearly understand three major levels of mental health stigma-structural (e.
View Article and Find Full Text PDFJ Colloid Interface Sci
December 2024
College of Marine Life Sciences, Ocean University of China, No. 5 Yushan Road, Qingdao 266003, China. Electronic address:
Emergency bleeding presents significant challenges such as high blood flow and rapid hemorrhaging. However, many existing hemostatic bandages face limitations, including the uncontrolled release of hemostatic agents, insufficient mechanical strength, poor adhesion, and complex manufacturing processes. To address these limitations, we developed a multifunctional hydrogel bandage for emergency hemostasis using a one-pot synthesis method.
View Article and Find Full Text PDFFront Pharmacol
December 2024
Department of Anesthesiology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Background: The combination of esketamine and propofol has become a common choice for total intravenous anesthesia in hysteroscopic procedures. However, the optimal effective dose has not yet been determined. The aim of this study was to determine the median effective dose (ED) and 95% effective dose (ED) of esketamine compounded with propofol for painless hysteroscopy.
View Article and Find Full Text PDFFront Surg
December 2024
Department of Radiology, Shaoxing Second Hospital, Shaoxing, Zhejiang, China.
Introduction: Retroperitoneal hematoma with ongoing hemorrhage is a rare but critical condition following blunt abdominal trauma, requiring urgent evaluation and management. This case details a large retroperitoneal hematoma in the right iliac fossa caused by a rupture of the deep circumflex iliac artery (DCIA), successfully treated with transcatheter arterial embolization.
Case Description: A 66-year-old female presented to our hospital six hours after an electric tricycle accident with dizziness, fatigue, hypotension (80/50 mmHg), and tachycardia (105 beats/min).
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