Objectives: This study examined the effectiveness of Byrd's EarWell system for the treatment of auricular helix adhesion.
Methods: The newborns with helix adhesion were treated with ear molding. The photos of pinna were taken before, during, and after the treatment. The immediate and long-term outcomes, as well as the complications, were assessed by two independent plastic surgeons.
Study Design: A retrospective study. Data on family history, neonatal weight, gestational age, delivery method, laterality, gender, age of initiating treatment, medical comorbidities, duration of treatment, and follow-up time were collected.
Study Site And Period: From 2019 to 2021, infants treated with the EarWell System in the Eye and ENT Hospital of Fudan University were enrolled in this study.
Results: A total of 46 newborns (66 ears) with helix adhesion were included. The average onset time of treatment was 4.57 ± 3.63 weeks. The average duration of treatment was 7.40 ± 2.05 weeks. 97.0% ears' (64/66) immediate results were excellent or good. During long-term follow-up, 95.5% ears achieved excellent or good outcomes. Age of initiation treatment significantly affected immediate (= 0.001) and long-term (= 0.004) outcomes.
Conclusions: EarWell System was an effective method to correct auricular helix adhesion. Using this approach, patients with helix adhesion could avoid surgeries. Age of initiation treatment was the predictor of successful correction.
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http://dx.doi.org/10.3389/fped.2022.990629 | DOI Listing |
Med Oncol
December 2024
Institute of Infectious Diseases, Southwest Hospital, Army Medical University, Chongqing, China.
Hepatocellular carcinoma (HCC) is a highly malignant cancer and lacks effective therapeutic targets. The role of LIM/homeobox protein Lhx3 (LHX3) has been extensively studied in various tumor tissues, where it has been identified as a promoter of tumorigenesis and malignancy. However, the specific functional role and potential mechanism of LHX3 in human HCCs are not clearly clarified.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
College of Food and Bioengineering, Henan University of Science and Technology, 471023 Luoyang, Henan, China; Henan Province Engineering Research Center of Agricultural Products Processing Equipment, 471000 Luoyang, China. Electronic address:
This study investigated the effects of chlorogenic acid (CA) with different levels (0.5 %-2.0 %) on the printing accuracy, micro-structure, rheological properties, thermodynamic properties, texture, digestion characteristics, and other indicators of sweet potato starch (SPS).
View Article and Find Full Text PDFPLoS Pathog
December 2024
Structural Studies Division, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, United Kingdom.
Type IV pili (T4Ps) are abundant in many bacterial and archaeal species, where they play important roles in both surface sensing and twitching motility, with implications for adhesion, biofilm formation and pathogenicity. While Type IV pilus (T4P) structures from other organisms have been previously solved, a high-resolution structure of the native, fully assembled T4P of Pseudomonas aeruginosa, a major human pathogen, would be valuable in a drug discovery context. Here, we report a 3.
View Article and Find Full Text PDFJ Sci Food Agric
December 2024
School of Agriculture, Food and Ecosystem Sciences, University of Melbourne, Parkville, Victoria, Australia.
Background: Given the composition of rice and its lack of gluten proteins, rice flour fails to form a cohesive and elastic dough when mixed directly with water. Consequently, many rice products rely on rice sheets (RS) made by rolling cooked rice dough. Limited research exists on how the rolling process impacts the properties and structure of cooked indica rice dough.
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