AI Article Synopsis

  • The study analyzes clinical and epidemiological data of CNS tumors in Uyghur children from a major hospital in Xinjiang over a 9-year period (2013-2021).
  • A total of 243 children (ages 0-17) were examined, with findings indicating that 59.26% had supratentorial tumors and 53.09% were low-grade tumors, predominantly affecting rural children.
  • The research revealed a male-to-female ratio of 1.43:1 and identified a peak incidence age between 6 to 8 years, reflecting specific patterns of CNS tumors in this population.

Article Abstract

Purpose: Retrospective analysis of clinical and epidemiological characteristics of central nervous system (CNS)tumors in Uyghur children from a single center in Xinjiang.

Methods: Between January 2013 and December 2021, 243 children (0-17 years old) with a clear pathological type of CNS tumor are collected and analyzed for tumor size, grade, and category, as well as their relationship with the child's gender, age, and region of origin according to the 2021 edition of the new WHO CNS tumor classification.

Outcome: The 243 cases of CNS tumors in Uyghur children are predominantly from rural areas, with 144 cases (59.26%) of supratentorial tumors and 129 cases (53.09%) of low-grade tumors. With an overall male-to-female ratio of 1.43:1, a peak age of incidence of 6 to 8 years.

Concluding: The present study is based on a 9-year analysis of pediatric CNS data from a single center, and the center is the largest tertiary hospital in Xinjiang with large numbers of admitted patients, which may reflect some extent the clinical characteristics and epidemiological features characteristics of pediatric CNS tumors in Uyghur in Xinjiang.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715407PMC
http://dx.doi.org/10.1007/s00381-022-05766-3DOI Listing

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