Trends in neck of femur fracture incidence in EU15+ Countries from 1990-2017.

Injury

Medical Data Research Collaborative, London W2 1NY, UK; Brigham and Women's Hospital, Boston, MA, USA; Imperial Vascular Unit, Imperial College Healthcare NHS Trust, London, UK.

Published: February 2023

AI Article Synopsis

  • Neck of femur fractures (NOFF) are a major health issue with serious socio-economic impacts and high rates of morbidity and mortality, and their incidence has been tracked in the Global Burden of Disease database without cross-country comparisons until now.
  • A study analyzed age-standardized incidence rates (ASIR) of NOFF across 19 European Union countries from 1990 to 2017, finding trends of incidence increases and changes in rates by country and gender through statistical methods.
  • Results showed that 58% of countries experienced rising NOFF ASIRs, with females having generally higher rates than males, while Australia had the highest ASIRs and Mediterranean countries the lowest, highlighting significant gender disparities despite advancements in prevention strategies.

Article Abstract

Background: Neck of femur fractures (NOFF) pose significant socio-economic costs to society with a high degree of morbidity and mortality. Its incidence rate has been collated within the Global Burden of Disease (GBD) database; however, to date, no comparison across countries has been reported.

Methods: NOFF age-standardised incidence rates (ASIR) per 100,000 population were extracted from the GBD database for European Union (EU) 15+ countries over the period 1990 to 2017. Joinpoint regression analysis of the data identified trends in ASIR and associated estimated annual percentage changes (EAPC). These were analysed by specified timeframe, country and gender.

Results: Of the 19 EU15+ countries, 11 (58%) had overall increases in NOFF ASIRs in 2017 compared to 1990. The median ASIRs were 240/100,000 and 322/100,000 for males and females, respectively, in 1990. By 2017, this had increased to 259/100,000 and 325/100,000, respectively. Females consistently had relatively higher NOFF ASIRs with a median gender fracture gap of 62/100,000 in 2017. Males had a higher percentage change in increasing ASIRs, with a smaller percentage change in decreasing ASIRs for all included countries. The highest national ASIRs was observed in Australia, followed by Finland and Belgium. Conversely the Mediterranean countries demonstrated the lowest ASIRs, closely followed by the USA.

Conclusion: Despite significant advances in primary and secondary hip fracture prevention strategies over the 28-year study period, significant increases in NOFF ASIRs among most EU15+ countries were observed, especially with respect to gender.

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Source
http://dx.doi.org/10.1016/j.injury.2022.11.038DOI Listing

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