AI Article Synopsis

  • Metabolic and cardiovascular diseases significantly impact global health, but advancements in genetics and technology are paving the way for new treatments.
  • The chapter emphasizes the CRISPR-Cas gene editing system while also exploring various online resources for conducting gene editing experiments.
  • It consolidates different gene editing strategies and tools with a focus on their potential applications in studying and treating metabolic and cardiovascular diseases.

Article Abstract

Metabolic and cardiovascular diseases are world-concerning pathologies that affect an important percentage of the population. Nowadays, advances in the genetic background of these diseases allow new approaches to models and therapies, as well as different gene edition trials. Furthermore, technological improvements in gene editing go along with the development of new online and biocomputational tools that provide us alternative ways to explore pathologies. In this chapter, historical gene editing methods are discussed but focusing on CRISPR-Cas system in detail and also online resources available to perform these types of experiments. Here, the different strategies for gene editing and their online tools are gathered, putting the light on its application in the study and treatment of cardiovascular and metabolic diseases.

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http://dx.doi.org/10.1007/978-981-19-5642-3_2DOI Listing

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