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Contralateral Nodal Metastasis from Tongue Malignancy. | LitMetric

Contralateral Nodal Metastasis from Tongue Malignancy.

Indian J Otolaryngol Head Neck Surg

Department of Statistics, CMC, Vellore, India.

Published: October 2022

Oral cavity is the most common site of cancer in India, tongue forms the most common single subsite. Neck node involvement plays an important prognostic role in disease-free survival and overall survival. Most of the nodal metastasis are occult and only an elective neck dissection can disclose the nodal metastasis, which is accepted only when the risk of metastasis exceeds 15-20%. Contralateral nodal metastasis(CLNM) are rarely analyzed due to sparse event.Retrospective analysis of data of patients who underwent surgery for carcinoma tougue with a curative intend between April 2017 and March 2019 were collected. Factors influencing CLNM in carcinoma tongue were studied.The study included 149 patients, with 102 men and 47 women. The mean age of study subjects was 51.5 ± 11.8 years. Thirteen (8.7%) patients had CLNM. With respect to tumor, advanced stage( < 0.001), floor of mouth involvement( = 0.001) and lesion crossing midline( < 0.001) had an increased risk of CLNM. Extranodal extension(ENE)( < 0.001) and lymphnode ratio( = 0.002) in ipsilateral node ratio influenced CLNM. Multivariant analysis showed that in addition to lesion crossing midline( = 0.03), ENE played significant role in CLNM ( < 0.001), with a risk of 12.8 times compared to no ENE. Suspicion of CLNM either clinically/radiologically was a good predictor of metastasis(p < 0.001).CLNM in tongue cancer was significantly influenced by lesion crossing midline and ENE. Contralateral neck dissection should be performed in any case with clinical/radiological suspicion of nodal involvement and above mentioned risk factors.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9702012PMC
http://dx.doi.org/10.1007/s12070-020-01921-xDOI Listing

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