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Exploring the Link Between Obligate Anaerobe-Related Dysbiosis and Prostate Cancer Development: A Pilot Study.
Cancers (Basel)
December 2024
Wolfson Institute of Population Health, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.
Background/objectives: Several independent studies have associated prostate cancer (PCa) with specific groups of bacteria, most of them reporting the presence of anaerobic or microaerophilic species such as (). Such findings suggest a prostate cancer-related bacterial dysbiosis, in a manner similar to the association between infection and gastric cancer. In an earlier exploratory study looking for such dysbiosis events, using a culturomics approach, we discovered that the presence of obligate anaerobes (OAs) along with was associated with increased prostate-specific antigen (PSA) levels in 39 participants.
View Article and Find Full Text PDFPrevalence and factors associated with female genital mutilation/cutting among Tanzanian women who gave birth in the five years prior to the survey: A population-based study.
PLoS One
January 2025
Department of Clinical Nursing, School of Nursing and Public Health, The University of Dodoma, Dodoma, Tanzania.
Background: Female Genital Mutilation/Cutting (FGM/C) poses a significant public health challenge in developing countries, leading to increased risks of adverse obstetric outcomes such as caesarean section, postpartum hemorrhage, episiotomy, difficult labor, obstetric tears/lacerations, instrumental delivery, prolonged labor, and extended maternal hospital stays. The study aimed to determine the prevalence and factors associated with FGM/C among Tanzanian women who had given birth within five years preceding the Survey.
Method: This study utilized an analytical cross-sectional design based on data from the 2015-2016 Tanzania Demographic and Health Survey and Malaria Indicators Survey (TDHS-MIS).
Exploratory Qualitative Study to Investigate Factors Influencing Men's Utilization of Sexual and Reproductive Health Services in Kwa-Zulu Natal.
Int J Environ Res Public Health
December 2024
School of Nursing and Public Health, College of Health Sciences, University of KwaZulu-Natal, Durban 4041, South Africa.
Sexual and reproductive health (SRH) is essential for men's health, but a large body of research has indicated that the underutilization of most SRH services by men is a persistent issue that needs to be addressed. Men's reluctance to access sexual and reproductive health services is one of the factors that leads to high morbidity and mortality rates among men, although their diseases may have been prevented or cured. This study aimed to explore factors that influence the decision of men who resided in men's hostels and who accessed urology clinics in KwaZulu-Natal to seek help for their sexual and reproductive health issues.
View Article and Find Full Text PDFExploring the relationship between medically unnecessary childhood penile circumcision and adult mental health.
Cult Health Sex
January 2025
Department of Psychology, Staffordshire University, Stoke-on-Trent, UK.
There is increasing recognition of the need to address the diverse experiences of individuals subjected to medically unnecessary, non-voluntary genital cutting in childhood. This includes children with intersex traits undergoing 'normalisation' surgeries and those with anatomically normative genitalia, such as female genital cutting or male circumcision. While most research on non-therapeutic childhood penile circumcision centres on the physical risks and benefits, far less attention has been given to the potential long-term mental health impacts, particularly from a psychotherapeutic perspective.
View Article and Find Full Text PDFEffect of Clonidine on Duration of High-Volume, Low-Concentration Caudal Epidurals.
Cureus
December 2024
Anesthesiology and Perioperative Medicine, Medical University of South Carolina, Charleston, USA.
Article Synopsis
- Caudal blocks are a pediatric anesthesia technique used to manage pain after circumcision; this study aimed to compare the duration of the block when using a high-volume, low-concentration (HVLC) local anesthetic with and without the addition of clonidine.
- The study included 129 children aged 0-3 years and measured the effectiveness of pain relief based on how long patients waited before needing additional acetaminophen; no significant differences were found between the clonidine and no-clonidine groups regarding pain management or emergence agitation.
- Overall, the addition of clonidine did not significantly improve the outcomes of HVLC caudal blocks for children undergoing circumcision.
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