AI Article Synopsis

  • Ganglioneuroma is a rare benign tumor that starts in the sympathetic ganglia, usually found in areas like the posterior mediastinum and adrenal gland, with occurrences in the parapharyngeal space being extremely rare.
  • The report discusses two adult male patients whose imaging and cytology did not identify a parapharyngeal mass before surgery, but they underwent successful tumor removal through a combined cervical and oral approach.
  • The study includes a review of English literature on parapharyngeal ganglioneuroma from the past 40 years, aiming to enhance the understanding of its diagnosis and treatment through the insights gained from these cases.

Article Abstract

Ganglioneuroma is a rare benign tumor originating in the sympathetic ganglia, composed of differentiated ganglion cells, nerve sheath cells, and nerve fibers, which tend to occur in the posterior mediastinum, adrenal gland, retroperitoneal, and other locations, occurring in the head and neck is relatively rare, and parapharyngeal space involvement is extremely rare. In our report, we present 2 adult male patients whose preoperative imaging and fine needle cytology did not confirm the diagnosis of a parapharyngeal space mass and who completely resected the tumor through a combined cervical and oral approach. Finally, pathology confirmed ganglioneuroma; we also reviewed the English articles on parapharyngeal ganglioneuroma over the past 40 years, and summarized the diagnostic and treatment characteristics of parapharyngeal ganglioneuroma in combination with our cases to improve understanding of the disease.

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http://dx.doi.org/10.1177/01455613221142658DOI Listing

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