Introduction: Dizziness is a common complaint by patients, yet it always presents as a diagnostic challenge to the attending clinician. An accurate diagnosis is essential to correctly administer the precise treatment regime, alleviate the symptoms, and improve the quality-of-life of patients who present with dizziness. A specialised vestibular clinic with a holistic approach of meticulous history-taking, complete physical examination, a collection of audiovestibular test battery, and facilities for vestibular rehabilitation was set up to assist in the management of these patients. This study aims to investigate the effect of vestibular clinic intervention on the symptoms and qualityof- life of patients who were managed in the vestibular clinic.
Materials And Methods: A total of 64 new patients who were managed in the vestibular clinic were selected and the validated Malay - Vestibular Rehabilitation Benefit Questionnaire (My-VRBQ) was completed during the first and follow-up visits to measure the changes in symptoms and quality-of-life before and after receiving care at the vestibular clinic.
Results: Our study showed that there was a positive effect of vestibular clinic intervention on the symptoms and quality-of-life of patients who were managed by the vestibular clinic. Statistically significant improvements were seen in the total My-VRBQ scores, symptoms scores, and quality-of-life scores. The subscale scores of dizziness, anxiety, and motion-provoked dizziness also showed statistically significant improvement among the patients who received care at the vestibular clinic.
Conclusion: This indicates that the vestibular clinic was an essential part of the work-up, diagnosis, and treatment of patients with dizziness; and a specialised vestibular clinic was able to bring about positive outcomes in the symptoms and quality-of-life of patients with balance disorders.
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Eur Arch Otorhinolaryngol
January 2025
Department of Otorhinolaryngology and Head and Neck Surgery, Division of Balance Disorders, School for Mental Health and Neuroscience (MHENS), Maastricht University Medical Centre, Maastricht, The Netherlands.
Purpose: It is hypothesized that a vestibular implant should re-establish baseline activity of the ampullary nerves. Use of a constant baseline stimulation potentially allows encoding of bi-directional head movements, through the addition of signal modulations. Effective stimulation of the vestibular nerves depends on the ability to acclimate to this baseline signal.
View Article and Find Full Text PDFHair cells (HCs) are essential for vestibular function, and irreversible damage to vestibular HCs in mammals is closely associated with vertigo. The stimulation of HC regeneration through exogenous gene delivery represents an ideal therapeutic approach for restoring vestibular function. Overexpression of Atoh1, Pou4f3, and Gfi1 (collectively referred to as APG) has demonstrated efficacy in promoting HC regeneration in the cochlea.
View Article and Find Full Text PDFCan Assoc Radiol J
January 2025
North York General Hospital, Toronto, ON, Canada.
The Canadian Association of Radiologists (CAR) Central Nervous System Expert Panel is made up of physicians from the disciplines of radiology, emergency medicine, neurosurgery, and neurology, a patient advisor, and an epidemiologist/guideline methodologist. After developing a list of 24 clinical/diagnostic scenarios, a rapid scoping review was undertaken to identify systematically produced referral guidelines that provide recommendations for one or more of these clinical/diagnostic scenarios. Recommendations from 55 guidelines and contextualization criteria in the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) for guidelines framework were used to develop 51 recommendation statements across the 24 scenarios.
View Article and Find Full Text PDFPhys Med Biol
January 2025
Radiotherapy and Radiosurgery department, Iatropolis Clinic, 54 Ethnikis Antistaseos ave., Athens, Attica, 15231, GREECE.
Using the concept of biologically effective dose (BED), the effect of sublethal DNA damage repair (SLR) on the bio-efficacy of prolonged radiotherapy treatments can be quantified (BED). Such treatments, lasting more than 20 min, are typically encountered in stereotactic radiosurgery (SRS) applications using the CyberKnife (CK) and Gamma knife systems. Evaluating the plan data from 45 Vestibular Schwannoma (VS) cases treated with single fraction CK-SRS, this work demonstrates a statistically significant correlation between the marginal BEDSLR delivered to the target (m-BEDSLR) and the ratio of the mean collimator size weighted by the fraction of total beams delivered with each collimator ((_w^m)Cs), to the tumor volume (Tv).
View Article and Find Full Text PDFJ Head Trauma Rehabil
January 2025
Author Affiliations: Department of Physical Medicine and Rehabilitation (Drs Wyrwa, Burke, Forster, and Kinney), Departments of Physical Medicine and Rehabilitation, Psychiatry, and Neurology (Dr Brenner), University of Colorado, Anschutz Medical Campus, Aurora, Colorado; and VA Rocky Mountain Mental Illness Research, Education, and Clinical Center (MIRECC) (Dr Brenner, Mr Yan, Ms Schneider, Mr King, and Drs Forster and Kinney), Aurora, Colorado.
Objective: To examine whether neurobehavioral symptoms mediate the relationship between comorbid mental health conditions (major depressive disorder [MDD] and/or posttraumatic stress disorder [PTSD]) and participation restriction among Veterans with mild traumatic brain injury (mTBI).
Setting: Veterans Health Administration (VHA).
Participants: National sample of Veterans with mTBI who received VHA outpatient care between 2012 and 2020.
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