Background: Serrated polyps have been recognized as the important premalignant lesions. In this study, we aimed to analyze the clinicopathological features of sessile serrated polyps and determine the association between sessile serrated polyps and synchronous advanced adenomas.

Methods: Consecutive patients undergoing diagnostic or therapeutic colonoscopies (including 156 681 diagnostic colonoscopies) from 2011 to 2019 were included.

Results: A total of 958 patients, including 699 (73%) males, were detected with at least 1 sessile serrated polyp, and 65.9% (n = 658) of sessile serrated polyps were located in the distal colon. Advanced serrated lesions accounted for 9.1% (n = 91) of all the sessile serrated polyp (n = 999). The types of SSP included flat type (953/999, 95.4%) and sub-pedunculated or pedunculated type (46/999, 4.6%). Meanwhile, there was no obvious evidence supporting the association between advanced adenomas and characteristics of advanced serrated lesions or sessile serrated polyps.

Conclusion: Sessile serrated polyps seem to be more frequently seen in the distal colon of men in this study. However, more evidence is required to confirm the actual distribution of sessile serrated polyp in colon among Chinese people. There is still much room for improvement of sessile serrated polyp detection rate, and more importance should be attached to sessile serrated polyp both for pathologists and endoscopists.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081119PMC
http://dx.doi.org/10.5152/tjg.2022.22027DOI Listing

Publication Analysis

Top Keywords

sessile serrated
44
serrated polyps
24
serrated polyp
20
serrated
14
sessile
11
clinicopathological features
8
features sessile
8
distal colon
8
advanced serrated
8
serrated lesions
8

Similar Publications

Continuing Medical Education Questions: August 2024.

Am J Gastroenterol

August 2024

US Navy, Washington, DC, USA.

Article Title: Adenomas and Sessile Serrated Lesions in 45-49-Year-Old Individuals Undergoing Colonoscopy: A Systematic Review and Meta-Analysis.

View Article and Find Full Text PDF

Superficial Serrated Adenoma: A Rare Case of Sigmoid Polyp With Malignant Potential.

Cureus

December 2024

Department of Digestive Disease, Xiamen Chang Gung Hospital, Hua Qiao University, Xiamen, CHN.

We present the case of a 68-year-old woman who underwent complete endoscopic resection of a superficial serrated adenoma (SuSA). Due to its rarity and limited case reports, SuSA is often misdiagnosed as a hyperplastic lesion without malignant potential, leading to missed diagnoses. A polypoid lesion was identified in the sigmoid colon during the initial endoscopic evaluation, where it was initially classified as a sessile serrated lesion (SSL).

View Article and Find Full Text PDF

Background: Iron deficiency anaemia (IDA) related to occult gastrointestinal tract (GIT) blood loss is associated with high rates of GIT malignancies. Major society guidelines recommend bidirectional endoscopic evaluation for all men and post-menopausal women with newly diagnosed, unexplained IDA. However, in patients prescribed direct oral anticoagulants (DOACs), the endoscopic yield, specifically the rate of high-risk findings, including colorectal cancers (CRCs) and advanced adenomas (AAs), is unknown.

View Article and Find Full Text PDF

Background: Efforts to improve colonoscopy have recently focused on improving adenoma detection through individual interventions. We evaluated an optimized computer-assisted technique (CADopt) versus standard colonoscopy.

Methods: A prospective randomized controlled trial was conducted enrolling adults (45-80 years) undergoing elective colonoscopy.

View Article and Find Full Text PDF

Background: Colorectal cancer (CRC) is the second leading cause of cancer death worldwide. Early detection of precursor lesions or early-stage cancer could hamper cancer development or improve survival rates. Liquid biopsy, which detects tumor biomarkers, such as mutations, in blood, is a promising avenue for cancer screening.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!