AI Article Synopsis
- The study investigates specific genetic alleles (L1014F, L1014S, L1014C, and G119S) linked to insecticide resistance in a malaria vector in Turkey.
- Researchers collected 60 female mosquitoes from three provinces and used special techniques to test for these alleles.
- The results showed a low presence of the L1014S allele in the studied populations, while the other mutations (L1014F, L1014C, G119S) were not detected at all.
Article Abstract
Objective: The study aims to determine the presence of L1014F, L1014S, L1014C alleles, which are responsible for knockdown resistance and G119S alleles, which are responsible for acetylcholinesterase insensitivity in , the secondary vector of malaria in Turkey.
Methods: In this study, 60 adult females were collected from Aydın, Denizli, and Muğla provinces. Then, allele-specific primers for L1014F, L1014S, and L1014C alleles, and the G119S allele were designed. The presence of these alleles was screened in three populations by allele-specific polymerase chain reaction.
Results: Although L1014S allele frequency was too low in Aydın, Muğla, and Denizli populations, neither L1014F and L1014C nor G119S mutations were found in any population.
Conclusion: In this study, L1014S mutation was detected for the first time in the Aegean populations.
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| http://dx.doi.org/10.4274/tpd.galenos.2022.20592 | DOI Listing |
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