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Inherently acidic films based on chitosan lactate-doped starches and pullulan as carries of nisin: A comparative study of controlled-release and antimicrobial properties. | LitMetric

AI Article Synopsis

  • Nisin (NIS) was added to edible films made from chitosan lactate and various starch blends, revealing that higher NIS concentrations allowed for more diffusion-driven release.
  • The starch-based films had limited solubility compared to fully dissolvable carriers, resulting in a slower and incomplete NIS release, with half-release times differing widely (under 1 minute to around 13 hours).
  • The NIS-enhanced films exhibited antibacterial properties against specific pathogens and improved UV-blocking, though the 0.2% NIS concentration reduced the tensile strength of the films by about 17-32%.

Article Abstract

Nisin (NIS) Z was incorporated (0.05 %, 0.1 %, 0.2 %) into edible films based on chitosan lactate (CHL) and 75/25 blends of polysaccharides (corn starch (CS), wheat starch (WS), oxidized potato starch (OPS), pullulan (PUL)) with CHL. The increase in the NIS/polymer ratio promoted the diffusion-driven release. Compared with the fully dissolvable CHL and PUL/CHL carriers, the starch/CHL films had limited solubility (≈27-37 %) and, consequently, ensured slower/incomplete release of NIS. The assayable NIS half-release times, determined in water, ranged from <1 min to ∼13 h. Probably due to the similar pH (≈4.5), there were generally no large differences between the antibacterial activities of the formulations. The NIS-supplemented systems limited the growth of some pathogens (B. cereus, L. monocytogenes, S. aureus), phytopathogens (P. carotovorum), and bacterial starter cultures. The NIS improved the UV-blocking ability of the films, but the 0.2 % NIS addition weakened (by ≈17-32 %) the tensile strength of most of the films.

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Source
http://dx.doi.org/10.1016/j.foodchem.2022.134760DOI Listing

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