: Silent brain infarcts (SBI) are thromboembolic complications associated with cardiac surgery, diagnostic angiography, and percutaneous interventions. Serum neuron-specific enolase (NSE) is the proven biomarker for measuring neuronal damage. This study aimed to evaluate the incidence of SBI, defined as elevated NSE after coronary chronic total occlusion (CTO) intervention and elective coronary stenting. : The study population consisted of two patient groups: the CTO group included consecutive patients with coronary CTO intervention, and the control group consisted of patients who underwent elective coronary intervention. NSE blood levels were measured before and 12-18 h after the procedure. NSE blood levels of >20 ng/mL were considered SBI. : A total of 108 patients were included in the study. Of these, 55 (50.9%) had SBI after the procedure. The SBI rate was 59.7% in the CTO group and 39.1% in the control group. Patients with SBI were more likely to have diabetes mellitus, hyperlipidemia, higher HbA1c, higher total stent length, and longer procedural time. Multivariate logistic regression analysis showed that CTO procedure (odds ratio [OR]: 3.129; 95% confidence interval [CI]: 1.246-7.858; < 0.015) and diabetes mellitus (OR: 2.93; 95% CI: 1.185-7.291; < 0.020) are independent predictors of SBI. : Our data suggest that SBI occurs more frequently after CTO intervention than after non-CTO intervention. Intervention complexity and patient clinical characteristics may explain the increased incidence.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/14017431.2022.2150786 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: A randomized trial.
Elife
January 2025
Department of Neurosurgery, Washington University School of Medicine, Springfield, United States.
Background: Subarachnoid hemorrhage (SAH) is characterized by intense central inflammation, leading to substantial post-hemorrhagic complications such as vasospasm and delayed cerebral ischemia. Given the anti-inflammatory effect of transcutaneous auricular vagus nerve stimulation (taVNS) and its ability to promote brain plasticity, taVNS has emerged as a promising therapeutic option for SAH patients. However, the effects of taVNS on cardiovascular dynamics in critically ill patients, like those with SAH, have not yet been investigated.
View Article and Find Full Text PDFSex Differences in Processing Emotional Speech Prosody: Preliminary Findings from a Multi-Feature Oddball Study.
Brain Sci
November 2024
Department of Speech-Language-Hearing Sciences, University of Minnesota, Minneapolis, MN 55455, USA.
Background/objectives: Emotional prosody, the intonation and rhythm of speech that conveys emotions, is vital for speech communication as it provides essential context and nuance to the words being spoken. This study explored how listeners automatically process emotional prosody in speech, focusing on different neural responses for the prosodic categories and potential sex differences.
Methods: The pilot data here involved 11 male and 11 female adult participants (age range: 18-28).
The power of music: impact on EEG signals.
Psychol Res
January 2025
Department of Neurology and Clinical Neurophysiology Unit, Faculty of Medicine-Cairo University, Cairo, Egypt.
Article Synopsis
- Music can influence our attention and cognitive functions without us realizing it, and it triggers neurotransmitter release in the brain that improves our mood and thinking.
- This study examined how two types of music—Egyptian folk and classical—affected brain activity in 76 participants, revealing that different music genres activate distinct cortical areas in the brain, particularly influencing the frontal and occipital regions.
- Findings showed that folk music led to a significant decrease in brain activity, indicating a relaxed state that could temporarily reduce cognitive abilities, while classical music was linked to an overall more relaxed brain state.
Oxidative Stress Biomarkers in Hypertension.
Curr Med Chem
January 2025
3rd Department of Cardiology, General Hospital of Thoracic Diseases 'Sotiria', National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Arterial hypertension is a silent and progressive disease with deleterious vascular implications on all target organs, including the heart, the brain, the kidneys, and the eyes. Oxidative stress, defined as the overproduction of Reactive Oxygen Species (ROS) over antioxidants, is capable of deteriorating not only the normal endothelial but also the cellular function with further cardiovascular implications. Xanthine oxidase activity, NADPH oxidase overexpression, and ROS production lead to hypertension and high arterial tone, culminating in end-organ damage.
View Article and Find Full Text PDFRisk Factors for Silent Brain Infarction in Nonvalvular Atrial Fibrillation Patients with Low CHA2DS2-VASc Score.
Curr Neurovasc Res
December 2024
Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Article Synopsis
- Silent Brain Infarction (SBI) is associated with cognitive decline and increased stroke risk, particularly in patients with nonvalvular atrial fibrillation (NVAF) having a low CHA2DS2-VASc score.
- In a study of 301 low-risk NVAF patients, significant differences in blood parameters and echocardiography results were found between those with and without SBI, with Platelet-To-Lymphocyte Ratio (PLR) and left atrial diameter (LAD) identified as independent risk factors.
- The study established that both PLR and LAD have diagnostic value for SBI, with a combined area under the curve (AUC) indicating moderate predictive ability for identifying patients at
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!