Early differences in sensory responsiveness may contribute to difficulties with communication among autistic children; however, this theory has not been longitudinally assessed in infants at increased familial versus general population-level likelihood for autism (Sibs-autism vs. Sibs-NA) using a comprehensive battery of sensory responsiveness and communication. In a sample of 40 infants (20 Sibs-autism, of whom six were later diagnosed with autism; 20 Sibs-NA), we tested (a) associations between sensory responsiveness at 12-18 months and communication 9 months later and (b) evaluated whether such associations were moderated by sibling group, autism diagnosis, or age. We found negative zero-order correlations between sensory responsiveness (i.e., caregiver reported hyperresponsiveness and hyporesponsiveness; an observational measure of hyperresponsiveness) and later communication. Additionally, caregiver reported sensory seeking was negatively associated with later expressive communication only in Sibs-NA. Limitations include our relatively small sample size of infants diagnosed with autism. Implications for future research are discussed.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707174 | PMC |
| http://dx.doi.org/10.1007/s10803-022-05817-3 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Unlabelled: Sensory filtering - prioritizing relevant stimuli while ignoring irrelevant ones - is crucial for animals to adapt and survive in complex environments. While this phenomenon has been primarily studied in organisms with complex nervous systems, it remains unclear whether simpler organisms also possess such capabilities. Here, we studied temporal information processing in , a freshwater planarian flatworm with a primitive nervous system.
View Article and Find Full Text PDFRecent work has claimed that most apparently cross-modal responses in sensory cortex are instead caused by the face movements evoked by stimuli of the non-dominant modality. We show that visual stimuli rarely trigger face movements in awake mice; when they occur, such movements do not explain visual responses in auditory cortex; and in simultaneous recordings, face movements drove artifactual cross-modal responses in visual but not auditory cortex. Thus face movements do not broadly explain cross-modal activity across all stimulus modalities.
View Article and Find Full Text PDFIn sensory and mid-level regions of the brain, stimulus information is often topographically organized; functional responses are arranged in maps according to features such as retinal coordinates, auditory pitch, and object animacy or size. However, such organization is typically measured during stimulus input, e.g.
View Article and Find Full Text PDFHierarchical representations of relative numerical magnitudes in the human frontoparietal cortex.
Nat Commun
January 2025
Center for Information and Neural Networks (CiNet), Advanced ICT Research Institute, National Institute of Information and Communications Technology, Suita, Japan.
The ability to estimate numerical magnitude is essential for decision-making and is thought to underlie arithmetic skills. In humans, neural populations in the frontoparietal regions are tuned to represent numerosity. However, it remains unclear whether their response properties are fixed to a specific numerosity (i.
View Article and Find Full Text PDFFoxm1 promotes differentiation of neural progenitors in the zebrafish inner ear.
Dev Biol
January 2025
Biology Department, Texas A&M University, College Station, TX 7843-3258. Electronic address:
During development of the vertebrate inner ear, sensory epithelia and neurons of the statoacoustic ganglion (SAG) arise from lineage-restricted progenitors that proliferate extensively before differentiating into mature post-mitotic cell types. Development of progenitors is regulated by Fgf, Wnt and Notch signaling, but how these pathways are coordinated to achieve an optimal balance of proliferation and differentiation is not well understood. Here we investigate the role in zebrafish of Foxm1, a transcription factor commonly associated with proliferation in developing tissues and tumors.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!