Effect of SARS-CoV-2 infection and pandemic period on healthcare-associated infections acquired in intensive care units.

Clin Microbiol Infect

REA-REZO (Surveillance, Infections & Antibiotic Resistance Network in ICU), Hospices Civils de Lyon Groupement Sud, St Genis Laval, France; Public Health, Epidemiology and Evolutionary Ecology of Infectious Diseases, Centre International de Recherche en Infectiologie Lyon, France; CPias Auvergne Rhône-Alpes, Hôpital Henry Gabrielle, Hospices Civils de Lyon, France.

Published: April 2023

AI Article Synopsis

Article Abstract

Objectives: To compare the occurrence of healthcare-associated infections acquired in intensive care units (HAI-ICUs) in France among patients with COVID-19 and those without it in 2020 and the latter with that in patients before the COVID-19 pandemic.

Methods: Multicentre HAI-ICU surveillance network (REA-REZO) data were used to identify 3 groups: 2019 patients (2019Control), a COVID-19 group (2020Cov), and a non-COVID-19 group (2020NonCov). The primary outcome was the occurrence of HAI-ICU (ventilator-associated pneumonia [VAP], bloodstream infections [BSIs], catheter-related bacteraemia). Standardized infection ratios of VAP were calculated for each quarter in 2020 and compared with those in 2019.

Results: A total of 30 105 patients were included in 2020: 23 798 in the 2020NonCov group, 4465 in 2020Cov group, and 39 635 patients in the 2019Control group. The frequency of VAP was strikingly greater in the 2020Cov group: 35.6 (33.4-37.8) episodes/1000 days of mechanical ventilation versus 18.4 (17.6-19.2) in the 2020NonCov group. VAP standardized infection ratio was high in 2020 patients, particularly during the 2 quarters corresponding to the 2 waves. BSI/1000 days were more frequent in the 2020Cov group (6.4% [6.4-6.4%] vs. 3.9% [3.8-3.9%] in the 2020NonCov group). VAP and BSI were also more frequent in the 2020NonCov group than in the 2019Control group. The microbial epidemiology was only slightly different.

Discussion: The data presented here indicate that HAI-ICUs were more frequent during the COVID-19 period, whether the patients were admitted for COVID-19 or, to a lesser extent, for another cause. This implies that managing patients with severe disease in a pandemic context carries risks for all patients.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613804PMC
http://dx.doi.org/10.1016/j.cmi.2022.10.023DOI Listing

Publication Analysis

Top Keywords

2020noncov group
16
2020cov group
12
group
11
patients
9
healthcare-associated infections
8
infections acquired
8
acquired intensive
8
intensive care
8
care units
8
patients covid-19
8

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!