Duchenne muscular dystrophy involves the myocardium and causes arrhythmia: Case report.

Front Cardiovasc Med

Department of Cardiovascular Medicine, The First Hospital of Jilin University, Changchun, China.

Published: November 2022

Background: Patients with muscular dystrophy have mutations in the gene that can lead to severe muscle wasting, respiratory issues or heart failure between ages 30 and 40. Currently, there is no effective treatment for DMD-induced heart failure.

Case Presentation: We report a patient with recurrent unexplained fever and muscle soreness was definitely diagnosed with DMD. An analysis of the patient's genetics revealed a nonsense mutation (C.1207G > T). His DMD was treated with hormones. Also, the patient's fever is under control because of hormone therapy. However, as the disease progresses, the heart structure and function gradually change, and eventually malignant arrhythmias occur.

Conclusion: We report a rare case of DMD involving the heart causing heart failure and malignant arrhythmia. Currently, no complete treatment is available for these patients, but our treatment regimen may benefit our patient and improve his outcomes.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681897PMC
http://dx.doi.org/10.3389/fcvm.2022.974843DOI Listing

Publication Analysis

Top Keywords

muscular dystrophy
8
heart failure
8
heart
5
duchenne muscular
4
dystrophy involves
4
involves myocardium
4
myocardium arrhythmia
4
arrhythmia case
4
case report
4
report background
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!