Ductal carcinoma in situ of the breast arising in a solitary intraductal papilloma.

Radiol Case Rep

Department of Radiology, Dubai Hospital, Dubai Health Authority, Dubai, United Arab Emirates.

Published: February 2023

AI Article Synopsis

  • * Although DCIS is often asymptomatic, it can sometimes present with nipple discharge or a lump, while benign conditions like intraductal papilloma may also cause similar symptoms.
  • * A case study of a 72-year-old woman showed she had serous and bloody discharge, and the histological examination confirmed she had intermediate-grade DCIS alongside an intraductal papilloma.

Article Abstract

Ductal disease is a broad group encompassing both benign and malignant entities which may overlap clinically and radiologically. Ductal carcinoma in situ (DCIS) is a noninvasive breast malignancy accounting for 20% of newly diagnosed breast cancer cases. It involves malignant epithelial cells confined to the duct(s). Although they are commonly diagnosed incidentally on screening mammography, DCIS may present with nipple discharge or a palpable lump. Benign diseases of the duct include intraductal papilloma and may present similarly with bloody or serous nipple discharge. Imaging evaluation will help in differentiating between the 2 entities and pathological examination will provide the final diagnosis. We present a case of a 72-year-old female who was presented with serous and bloody discharge and histology revealed intermediate grade ductal carcinoma in situ involving an intraductal papilloma.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691407PMC
http://dx.doi.org/10.1016/j.radcr.2022.11.014DOI Listing

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