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| http://dx.doi.org/10.3389/fpain.2022.1071810 | DOI Listing |
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Chronic neuropathic pain components in whiplash-associated disorders correlate with metabolite concentrations in the anterior cingulate and dorsolateral prefrontal cortex: a consensus-driven MRS re-examination.
Front Med (Lausanne)
July 2024
Instituto de Investigación Sanitaria de Castilla La Mancha (IDISCAM), Toledo, Spain.
Article Synopsis
- Whiplash injury (WHI) commonly occurs in car accidents, leading to chronic pain disorders, especially impacting areas in the brain responsible for pain processing.
- This study used magnetic resonance spectroscopy (MRS) to compare brain metabolite concentrations in individuals with chronic whiplash-associated disorders (WAD) and neuropathic pain (NP) to those without.
- Results showed higher glutamate in the anterior cingulate cortex (ACC) and lower total choline in the dorsolateral prefrontal cortex (DLPFC) in the WAD-NP group, suggesting specific metabolic changes linked to pain severity.
Editorial: Whiplash-associated disorder-advances in pathophysiology, patient assessment and clinical management.
Front Pain Res (Lausanne)
November 2022
RECOVER Injury Research Centre, The University of Queensland, Herston, QLD, Australia.
Confirming the geography of fatty infiltration in the deep cervical extensor muscles in whiplash recovery.
Sci Rep
July 2020
Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Previous preliminary work mapped the distribution of neck muscle fat infiltration (MFI) in the deep cervical extensor muscles (multifidus and semispinalis cervicis) in a small cohort of participants with chronic whiplash associated disorders (WAD), recovered, and healthy controls. While MFI was reported to be concentrated in the medial portion of the muscles in all participants, the magnitude was significantly greater in those with chronic WAD. This study aims to confirm these results in a prospective fashion with a larger cohort and compare the findings across a population of patients with varying levels of WAD-related disability one-year following the motor vehicle collision.
View Article and Find Full Text PDFDuring the American Physical Therapy Association's Combined Sections Meeting in New Orleans, LA in February 2018, JOSPT recognized the authors of the most outstanding research and clinical practice manuscripts published in JOSPT during 2017. The 2017 George J. Davies-James A.
View Article and Find Full Text PDFThe potential and perils of prognosticating persistent post-traumatic problems from a postpositivist perspective.
Spine J
August 2018
School of Physical Therapy, Western University, Rm. EC1443, 1201 Western Rd, London, Ontario, N6G 1H1, Canada.
Background Context: Predicting recovery after traumatic neck pain has become an active area of research but is moving in several different directions with currently little consensus on the important outcomes to predict or relevant variables to predict them.
Purpose: This editorial explores the current state of prognostic (risk)-based tools or algorithms for predicting the likelihood of chronic problems after acute axial trauma, with a focus on traumatic neck pain (ie, whiplash-associated disorder).
Study Design/setting: This paper has an editorial study design.
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