Chios mastic gum (CMG), the resin produced by the trunk of var Chia, has been used for culinary and medicinal purposes since antiquity. Despite the fact that species are widely distributed throughout the Mediterranean basin and in the circum-Mediterranean regions, CMG is a distinctive resin of the mastic trees grown exclusively in the southern part of the island of Chios. CMG has been used for centuries as a spice, a cosmetic, but its most important usage has been as a strong phytotherapeutic therapy, primarily for the management of gastrointestinal diseases. Recently, there are studies demonstrating that CMG has hypolipidemic, cardioprotective and antidiabetic properties. Therefore, the aim of the present review is to summarize the existing literature data regarding the potential beneficial effects of CMG on cardio-metabolic risk factors.
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http://dx.doi.org/10.4239/wjd.v13.i11.921 | DOI Listing |
Curr Gastroenterol Rep
January 2025
Department of Gastroenterology, St. Luke's University Health Network, Bethlehem, PA, USA.
Purpose Of Review: Inflammatory bowel disease (IBD) can cause significant psychological, physical, and economic burdens on patients and healthcare systems. Studies show over one-fifth of patients will seek nontraditional methods of treatment for managing their symptoms. Understanding the benefits - and potential harms - of these therapies is important to provide holistic and evidence-based care to our IBD patients.
View Article and Find Full Text PDFBiomolecules
December 2024
Department of Pharmacy, Division of Pharmacognosy and Natural Products Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece.
24-Masticadienonic acid (MNA) and 24-isomasticadienonic acid (IMNA) are the major triterpenic acids in Chios Mastic Gum (CMG), a resin derived from var. . Despite their promising pharmacological potential, limited information is available due to the complexity of isolating them in pure form.
View Article and Find Full Text PDFNutrients
September 2024
School of Nutritional Sciences and Wellness, The University of Arizona, Tucson, AZ 85721, USA.
Chios mastic gum (CMG) is a resin obtained from the var. tree that grows in the Mediterranean. For millennia, it has been renowned for its medicinal properties, but recently, CMG has gained attention due to its pronounced anti-inflammatory and antioxidative properties and its use in oral health, inflammatory bowel disease, cancer, and risk factors related to cardiovascular and metabolic diseases.
View Article and Find Full Text PDFKorean J Physiol Pharmacol
September 2024
Department of Oral Anatomy, School of Dentistry, Pusan National University, Yangsan 50612, Korea.
Nutrients
July 2024
Laboratory of Pharmacology, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Zografou, Greece.
Hypertension poses a significant global health burden and is associated with cardiovascular morbidity. Chios mastic gum (CMG), derived from var. , shows potential as a phytotherapeutic agent, due to its multifaceted beneficial effects.
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