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TCBGY net for enhanced wear particle detection in ferrography using self attention and multi scale fusion.
Sci Rep
December 2024
Merchant Marine College, Shanghai Maritime University, Shanghai, 201306, China.
The intelligent identification of wear particles in ferrography is a critical bottleneck that hampers the development and widespread adoption of ferrography technology. To address challenges such as false detection, missed detection of small wear particles, difficulty in distinguishing overlapping and similar abrasions, and handling complex image backgrounds, this paper proposes an algorithm called TCBGY-Net for detecting wear particles in ferrography images. The proposed TCBGY-Net uses YOLOv5s as the backbone network, which is enhanced with several advanced modules to improve detection performance.
View Article and Find Full Text PDFComputational design of potent dimeric phenylthiazole NS5A inhibitors for hepatitis C virus.
Sci Rep
December 2024
Bioinformatics Laboratory, College of Computing, University Mohammed VI Polytechnic, Ben Guerir, Morocco.
Hepatitis C virus (HCV) presents a significant global health issue due to its widespread prevalence and the absence of a reliable vaccine for prevention. While significant progress has been achieved in therapeutic interventions since the disease was first identified, its resurgence underscores the need for innovative strategies to combat it. The nonstructural protein NS5A is crucial in the life cycle of the HCV, serving as a significant factor in both viral replication and assembly processes.
View Article and Find Full Text PDFDental Status of the Bulgarian Population: The Influence of Barriers to Accessing Dental Care.
Cureus
November 2024
Dental Public Health, Faculty of Dental Medicine, Medical University - Sofia, Sofia, BGR.
Introduction Dental caries is the most common disease worldwide and affects more than 90% of Europeans. The dental status of a population is an important indicator of quality of life. Different factors act as barriers and can obstruct access to dental services.
View Article and Find Full Text PDFAmericans' support for future pandemic policies: insights from a national survey.
Health Aff Sch
December 2024
The de Beaumont Foundation, Bethesda, MD 20814, United States.
The arrival of bird flu (H5N1) is a poignant reminder of the need for public health leaders to understand Americans' evolving perspectives on pandemic mitigation policies. To guide response efforts, we conducted a nationally representative opinion survey among 1017 U.S.
View Article and Find Full Text PDFInPAS: An R/Bioconductor Package for Identifying Novel Polyadenylation Sites and Alternative Polyadenylation from Bulk RNA-seq Data.
Front Biosci (Schol Ed)
December 2024
Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
Background: Alternative cleavage and polyadenylation (APA) is a crucial post-transcriptional gene regulation mechanism that regulates gene expression in eukaryotes by increasing the diversity and complexity of both the transcriptome and proteome. Despite the development of more than a dozen experimental methods over the last decade to identify and quantify APA events, widespread adoption of these methods has been limited by technical, financial, and time constraints. Consequently, APA remains poorly understood in most eukaryotes.
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