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Application of the thrombin generation assay in patients with antiphospholipid syndrome: A systematic review of the literature.
Front Cardiovasc Med
March 2023
Coagulation Laboratory, Ghent University Hospital, Ghent, Belgium.
Background: The antiphospholipid syndrome (APS) is classified by the presence of antiphospholipid antibodies (aPL) and thrombotic and/or adverse obstetric outcomes. The diagnosis and risk assessment of APS is challenging. This systematic review investigated if the thrombin generation (TG) assay could be helpful for APS diagnosis and risk assessment.
View Article and Find Full Text PDFDiagnosis of Antiphospholid Syndrome Uncovered Co-occurrence of Myelodysplastic Syndrome: A Case Report.
Isr Med Assoc J
November 2022
epartment of Internal Medicine C, Rabin Medical Center (Beilinson Campus), Petah Tikva, Israel, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
[Prevalence and etiological profiles of atypical localization venous thrombosis : A descriptive multicenter study].
Ann Cardiol Angeiol (Paris)
October 2022
Service de Médecine Interne, Centre hospitalier Universitaire Joseph Raseta Befelatanana, Antananarivo, Madagascar.
Introduction: Venous thrombosis of unusual sites is much rarer than in the lower limbs and requires a rigorous etiological approach. The objective was to describe the clinical and progressive peculiarities of unusual localization venous thrombosis as well as their etiologies.
Patients And Methods: Multicenter descriptive retrospective study of hospitalized patient records in the two large Hospital Centers, Antananarivo, Madagascar between 2017 and 2020 in which the diagnosis of unusual venous thrombosis was confirmed by imaging.
A significant improvement of thromboses treated by a new oral anticoagulant in an 11-year-old girl with systemic lupus erythematosus associated antiphospholipid syndrome: A case report.
Lupus
July 2021
Department of Pediatrics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Pediatric venous thrombosis is associated with a variety of chronic diseases. Antiphospholipid syndrome (APS) is one of them and is commonly related to systemic lupus erythematosus (SLE). Warfarin is the mainstream of anticoagulation treatment in pediatric APS currently but it needs close monitoring and frequent dose adjustment.
View Article and Find Full Text PDFA Simplified Understanding of the Black Swan: Anti-phospholipid Antibody Syndrome.
JNMA J Nepal Med Assoc
February 2020
Department of Rheumatology, National Center for Rheumatic Diseases, Ratopul, Kathmandu, Nepal.
Anti-phospholipid Antibody Syndrome or Hugh's syndrome is a heterogeneous disorder, first fully described in 1980s. The syndrome is caused by the presence of specific antibodies against phospholipid binding plasma proteins in the serum of the patient, with or without underlying autoimmune diseases, that causes prolongation of tests of coagulation. High index of clinical suspicion is required for diagnosis of Anti-phospholipid Antibody Syndrome.
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