Biological Stratification of Invasive and Advanced Urothelial Carcinoma.

Urol Clin North Am

Department of Urologic Sciences, University of British Columbia, Gordon & Leslie Diamond Health Care Centre, Level 6, 2775 Laurel Street, Vancouver, BC V5Z 1M9, Canada. Electronic address:

Published: February 2023

Muscle-invasive urothelial carcinoma (UC) of the bladder remains a highly lethal malignancy. In this review the authors explore the underlying biology associated with the evolution from non-muscle-invasive UC to muscle-invasive and metastatic UC, with a special focus on the molecular stratification of UC and the potential of this stratification to be used for treatment selection.

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http://dx.doi.org/10.1016/j.ucl.2022.09.007DOI Listing

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