AI Article Synopsis
- Volume control in cells is a critical issue that has been widely discussed in scientific literature.
- Boyd-Shiwarski and colleagues identify that higher levels of molecular crowding lead to the condensation of WNK kinase, a key protein involved in this process.
- This condensation helps cells detect and adapt to decreases in their volume, highlighting a novel mechanism for cellular response to volume changes.
Article Abstract
Volume control is a fundamental challenge for all cells, the mechanisms of which have been long debated. In this issue of Cell, Boyd-Shiwarski et al. find that increased molecular crowding drives condensation of WNK kinase, allowing cells to sense and respond to cell volume loss.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197922 | PMC |
| http://dx.doi.org/10.1016/j.cell.2022.10.027 | DOI Listing |
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