Antifungal Properties of on species: A Systematic Review.

Background And Purpose: infections have increased significantly in the antimicrobial resistance era, and synthetic antifungal drugs have limitations. The present work aimed to review the antifungal properties of () as an herbal remedy.

Method: PubMed, Scopus, ScienceDirect, Web of Science, SID, Civilica, and Magiran databases were searched for the antifungal activity on , , dental biofilm, and clinical studies of on species.

Results: Overall, 33 articles evaluated the effect of on species and classified them into four groups, as follows in vitro (23), dental biofilm (6), in vivo (2), and clinical studies (3). All studies considered effective in reducing or even inhibiting the growth of species. NoMFC significant differences were seen in the effect of on susceptible compared to the resistant groups of in the studies. It was also influential in inhibiting and .

Conclusion: Considering the side effects and resistance of current antifungal drugs as well as the benefits of using herbal medicines, such as lower cost, less likely to develop drug resistance, the absence of side effects, and toxicity compared with chemical ones it is possible as a powerful alternative to replace or combine with the current antifungal for infection therapy along with other therapies.