Gout nodules (tophi) are formed by a chronic inflammatory reaction in tissues resulting in deposition of urate crystals. They are commonly seen in joints and surrounding tissues, subcutaneous tissues, as well as the pinna and kidney, and are characteristic manifestations of gout. Vocal cord tophi are rarely reported in the literature, and patients often present with hoarseness, progressive dysphagia, and other symptoms. We report a case of a vocal cord mass found by gastroscopy in a patient with a history of gout for more than 20 years. Postoperative pathological findings were vocal cord tophi. Tophi can have serious consequences and should be included in the differential diagnosis of laryngeal masses in patients with a history of gout. Therapy should involve a combination of systemic uric acid-lowering treatment and surgery to improve symptoms and reduce recurrence.
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http://dx.doi.org/10.1177/01455613221137225 | DOI Listing |
Cureus
December 2024
Otorhinolaryngology - Head and Neck Surgery Department, King Abdulaziz Specialist Hospital, Taif, SAU.
Vocal cord nodules (VCNs) can be treated with a variety of therapeutic approaches, with controversy regarding the optimal management. This review provides an overview of the most commonly used management strategies and their outcomes to enhance decision making. We conducted a systematic literature search on PubMed, Web of Science, and Scopus to include relevant original articles published in peer-reviewed journals from inception through April 2024.
View Article and Find Full Text PDFNatl J Maxillofac Surg
November 2024
Department of ENT, All India Institute of Medical Sciences (AIIMS), Deoghar, Jharkhand, India.
Exploring diverse biomaterials and implants in the ear, nose, and throat by understanding adverse effects and post-usage events. Literature was obtained from Scopus, PubMed, Google Scholar, and Web of Science. A comprehensive analysis was conducted on original research studies, case reports, and case series spanning from December 2010 to May 2022.
View Article and Find Full Text PDFWorld J Surg Oncol
January 2025
Department of Thoracic Surgery, University Hospitals Birmingham, Birmingham, UK.
A 34-year-old male patient with recently diagnosed with medullary thyroid carcinoma underwent total thyroidectomy and radical neck dissection, requiring sharp dissection to separate the tumour from the trachea. He required post operative intubation due to bilateral vocal cord paralysis. He developed ischaemic necrosis of the upper two thirds of the trachea presenting with marked surgical emphysema and an infective wound.
View Article and Find Full Text PDFCureus
January 2025
Anesthesiology and Pain and Palliative Medicine, Radboud University Medical Center, Nijmegen, NLD.
When a difficult airway is anticipated, awake tracheal intubation can be considered. Usually, low doses of sedatives are administered during this procedure for minimal sedation and anxiolysis, such as midazolam and remifentanil. The newly developed ultra-short-acting benzodiazepine remimazolam has a pharmacokinetic profile that is more suitable for titration during awake tracheal intubation than the long-acting midazolam.
View Article and Find Full Text PDFSisli Etfal Hastan Tip Bul
December 2024
Department of General Surgery, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Türkiye.
Objectives: The extent of the surgical treatment for Graves' disease (GD) has evolved from subtotal to total thyroidectomy. This study analyzes the extent of thyroidectomy for GD and its impact on recurrence and complications, focusing on the relationship between remnant thyroid tissue and recurrence in subtotal thyroidectomy, comparing our current approach with historic data spanning over three decades.
Methods: A retrospective analysis of 427 GD patients who underwent surgery at a tertiary hospital from 1988 to 2022.
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