AI Article Synopsis
- A new fluorescence probe was created to detect biothiols and hypochlorous acid in sequence.
- The probe uses FRET (Förster Resonance Energy Transfer) and only shows fluorescence when biothiols react first with RSHClO before hypochlorous acid.
- This ability allows it to imitate biological processes and is ideal for imaging environments where oxidizing and reducing substances can't exist together.
Article Abstract
An 'AND'-based ratiometric fluorescence probe for the sequential detection of biothiols and hypochlorous acid was developed. FRET was observed only when RSHClO reacted with biothiols before reacting with hypochlorous acid, a phenomenon that has been confirmed in aqueous solutions and cells. This feature enables the probe to mimic biological processes and is particularly suitable for imaging oxidizing and reducing substances that cannot coexist.
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| http://dx.doi.org/10.1039/d2cc05782d | DOI Listing |
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