Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net.

Comput Intell Neurosci

School of Computer Science and Engineering, Central South University, Changsha 410083, China.

Published: November 2022

One of the most prevalent malignant bone tumors is osteosarcoma. The diagnosis and treatment cycle are long and the prognosis is poor. It takes a lot of time to manually identify osteosarcoma from osteosarcoma magnetic resonance imaging (MRI). Medical image processing technology has greatly alleviated the problems faced by medical diagnoses. However, MRI images of osteosarcoma are characterized by high noise and blurred edges. The complex features increase the difficulty of lesion area identification. Therefore, this study proposes an osteosarcoma MRI image segmentation method (OSTransnet) based on Transformer and U-net. This technique primarily addresses the issues of fuzzy tumor edge segmentation and overfitting brought on by data noise. First, we optimize the dataset by changing the precise spatial distribution of noise and the data-increment image rotation process. The tumor is then segmented based on the model of U-Net and Transformer with edge improvement. It compensates for the limitations of U-semantic Net by using channel-based transformers. Finally, we also add an edge enhancement module (BAB) and a combined loss function to improve the performance of edge segmentation. The method's accuracy and stability are demonstrated by the detection and training results based on more than 4,000 MRI images of osteosarcoma, which also demonstrate how well the method works as an adjunct to clinical diagnosis and treatment.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678467PMC
http://dx.doi.org/10.1155/2022/9990092DOI Listing

Publication Analysis

Top Keywords

segmentation method
8
osteosarcoma mri
8
mri image
8
based transformer
8
transformer u-net
8
diagnosis treatment
8
mri images
8
images osteosarcoma
8
edge segmentation
8
osteosarcoma
7

Similar Publications

Drug Development.

Alzheimers Dement

December 2024

UCLA, Los Angeles, CA, USA.

Background: Reducing fibrous aggregates of protein tau is a possible strategy for halting progression of Alzheimer's disease (AD). Previously we found that in vitro the D-peptide D-TLKIVWC fragments tau fibrils from AD brains (AD-tau) into benign segments, whereas its six-residue analog D-TLKIVW cannot. However, the underlying fragmentation mechanism remains unknown, preventing the further development of this type of drug candidate for AD.

View Article and Find Full Text PDF

Background: Dementia, a growing health crisis, disproportionally affects persons from racial/ethnic backgrounds and individuals with comorbidities. Latelife change in cognition is complex and nonlinear, as well as differential for these individuals. These individuals are also largely underrepresented in clinical trials.

View Article and Find Full Text PDF

Dementia Care Research and Psychosocial Factors.

Alzheimers Dement

December 2024

Siemens Heathineers, Princeton, NJ, USA.

Background: The recent breakthrough in monoclonal antibody treatment for Alzheimer's disease (AD) has ushered in a new phase in AD healthcare. However, associated amyloid-related imaging abnormalities (ARIA) present a significant risk to patients, necessitating careful monitoring. Detection by radiologists can be challenging and may suffer from inconsistency.

View Article and Find Full Text PDF

Dementia Care Research and Psychosocial Factors.

Alzheimers Dement

December 2024

Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil.

Background: Caregivers of people with dementia (PwD) often experience the burden of caregiving and depressive symptoms that may be associated. PwD who experience a higher occurrence of neuropsychiatric symptoms often cause a greater burden on their caregivers due to the difficulty in managing these symptoms. Caregivers may transfer their feelings of frustration and exhaustion with caregiving through the way they communicate with the PwD.

View Article and Find Full Text PDF

Objectives: The size, shape, and contractility of the heart's atrial chambers have not been evaluated in fetuses with growth restriction (FGR) or who are small-for-gestational-age (SGA) as defined by the Delphi consensus protocol. This study aimed to examine the atrial chambers using speckle tracking analysis to identify any changes that may be specific for either growth disturbance.

Methods: Sixty-three fetuses were evaluated with an estimated fetal weight <10th percentile who were classified as FGR or SGA based on the Delphi consensus protocol.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!