Glabraquinone A and B, new anthraquinones from (Korth.) Valeton.

Nat Prod Res

Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia.

Published: April 2024

Two new anthraquinones, glabraquinone A and B (-) were isolated from the root of (Korth.) Valeton. In addition to the new glabraquinones, six known anthraquinones, that is, 1-hydroxy-2-methoxy-6-methylanthraquinone (), 1,2-dimethoxy-7-methylanthraquinone (), lucidin (), nordamnacanthal (), damnacanthal () and 2-carboxaldehyde-3-hydroxyanthraquinone ()) and an aromatic compound, that is, catechol diethyl ether () were isolated and characterized in this study. Compounds , and showed mild activity, reducing N2A cell viability to 77%, 82% and 77%, respectively, in anti-neuroblastoma assay.

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Source
http://dx.doi.org/10.1080/14786419.2022.2147932DOI Listing

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