AI Article Synopsis
- Balancing adequate immunosuppression with infection risk post-renal transplantation is challenging, particularly with comorbidities present.
- Although rare, invasive fungal infections can lead to significant complications and high death rates in kidney transplant patients due to intense immunosuppression and subtle symptoms.
- There is a need for evidence-based guidelines for managing fungal infections in renal transplants, as current approaches rely heavily on clinical judgment; this report details a case study of early-onset candidiasis in a transplanted kidney, including findings and treatment.
Article Abstract
Balancing adequate immunosuppression with the risk of infection after renal transplantation remains a challenge. The presence of comorbidities adds to the challenge. Although infrequent, invasive fungal infections result in high morbidity and mortality risk in renal transplant recipients. This can be attributed to the intense immunosuppression in the first 6 months after renal transplantation, minimal symptomatology and the high mortality associated with fungal infections.Due to minimal available evidence, clinical judgement guides management of graft candidiasis. There is a need to develop evidence-based management guidelines for the treatment of fungal infections in renal transplants. Here, we report a case of early-onset candidiasis in a transplanted kidney and present the histological findings, multidisciplinary discussions and treatment given.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685235 | PMC |
| http://dx.doi.org/10.1136/bcr-2022-250890 | DOI Listing |
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