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Food habit, physical activity and nutritional status of adolescents in selected schools of Madhyapur Thimi municipality, Nepal: A cross-sectional study.
PLOS Glob Public Health
January 2025
Central Department of Public Health, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal.
A dramatic rise in obesity is caused by unhealthy eating habits combined with lower levels of physical activity, and the under nutrition problem is still unresolved. Focusing on the nutritional needs of adolescents could be a significant step toward breaking the vicious cycle of malnutrition, chronic diseases, and poverty. This study aims to assess food habit, levels of physical activity and nutritional status of adolescents in Madhyapur Thimi Municipality, Bhaktapur.
View Article and Find Full Text PDFThe Associations of Dental and Periodontal Lesions with the Microvascular Complications in Patients with Type 2 Diabetes Mellitus: A Case-Control Study.
Life (Basel)
December 2024
Department of Diabetes, Nutrition and Metabolic Diseases, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Background: Diabetes mellitus is closely related to periodontal disease and dental lesions, disorders which through dental infection and metabolic imbalance become negatively potentiated and cause a vicious circle that is almost impossible to break. The aim of this research was to study if the severity of dental and periodontal lesions is related to the presence of microvascular complications and glycemic control in patients with type 2 diabetes mellitus (T2DM).
Methods: In total, 112 subjects with T2DM that underwent a dental evaluation were enrolled in this case-control study.
Dual-target nanotherapy for vascular endothelium and bone mesenchymal stem cells halt steroid-induced osteonecrosis of the femoral head progression.
J Control Release
January 2025
Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address:
Steroid-induced osteonecrosis of the femoral head (SANFH) is a common hip joint disease that imposes a heavy economic burden on society. Patients continue to experience bone necrosis even after discontinuing glucocorticoid therapy, and the specific mechanisms require further investigation. The results of this study demonstrate that exosomes secreted by damaged vascular endothelial cells in SANFH lesions may be a crucial factor leading to abnormal adipogenic differentiation of bone marrow stromal cells (BMSCs).
View Article and Find Full Text PDFAnalysis of the dynamic evolution of green technology innovation decision-making in the supply chain.
J Environ Manage
December 2024
School of Business Administration, Chongqing Vocational College of Light Industry, Chongqing, 400065, China. Electronic address:
Green technology innovation (GTI) breaks the vicious cycle of "economic development-environmental pollution," mitigating the supply chain carbon emissions. Previous research focused on exploring supply chain GTI decision-making in the discrete strategy space and ignored the effect of stochastic factors. This paper, grounded in the classical evolutionary game theory, explores the interaction mechanism of supply chain GTI decision-making between suppliers and manufacturers under stochastic interferences and in the continuous strategy space.
View Article and Find Full Text PDFInter- and intracellular mitochondrial communication: signaling hubs in aging and age-related diseases.
Cell Mol Biol Lett
December 2024
Department of Neurology, The Affiliated Hospital of Qingdao University, Qingdao, 266000, China.
Mitochondria are versatile and complex organelles that can continuously communicate and interact with the cellular milieu. Deregulated communication between mitochondria and host cells/organelles has significant consequences and is an underlying factor of many pathophysiological conditions, including the process of aging. During aging, mitochondria lose function, and mitocellular communication pathways break down; mitochondrial dysfunction interacts with mitochondrial dyscommunication, forming a vicious circle.
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