Selective Separation of Hazardous Chemicals from Vapor Phase by an Easily Accessible Breathing Coordination Polymer Derived from Terpyridyl/terephthalate Mixed Ligands.

Coordination polymers are extensively studied materials because of their various potential applications. Amongst them, breathing coordination polymers that are capable of exchanging lattice occluded guest molecules with other guests via single-crystal-to-single-crystal (SC-SC) fashion are particularly intriguing. Herein, we disclose an easily accessible breathing coordination polymer namely DMF@Zn-CP capable of exchanging as many as 23 guest molecules of various kinds in SC-SC fashion when the crystals of the coordination polymer were exposed to the corresponding vapor of the guests. Selectivity experiments revealed that it was also capable of separating selectively hazardous chemicals such as dichloro-methane, benzene and fluorobenzene from the corresponding complex mixture of vapors of halomethanes, aromatic hydrocarbons and halobenzenes. The breathing coordination polymer could also be exploited as drug delivery vehicle; slow and sustained release of anti-bacterial agents (benzyl alcohol/phenethyl amine) as guests against both gram positive and gram negative bacteria was evident in zone inhibition assays. A mixed ligand strategy wherein a nitrile containing terpyridyl ligand (L) and terephthalate (TA) co-ligand were reacted with Co(II)/Ni(II)/Zn(II) nitrate salts was adopted herein. Three coordination polymers namely MeOH@Co-CP, DMF/H O@Ni-CP and DMF@Zn-CP were isolated and characterized by single crystal X-ray diffraction. Studies revealed that only DMF@Zn-CP possessed the ability to breath in response to the vapors of the guests as stimuli.