This article describes a 23-year-old woman with bruising, hair loss, and stretch marks, which was found to be due to Cushing syndrome. Because of its nonspecific symptoms, this disease of hypercortisolism can be mistaken for other conditions.
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A Case of Noonan Syndrome and Kyrle's Disease: Coincidence or Causality?
Acta Dermatovenerol Croat
March 2024
Marco Brusasco, MD, University of Parma, Via Gramsci 14, Parma, Italy;
Article Synopsis
- A 39-year-old woman with Noonan Syndrome and a RAF1 mutation presented with itchy lesions on her limbs that developed two months prior, characterized by multiple dome-shaped papules.
- Blood tests showed no abnormalities, but a skin biopsy revealed features consistent with Kyrle's disease, a type of perforating dermatosis.
- The patient was treated with narrowband UVB phototherapy, resulting in complete resolution of symptoms despite leaving residual atrophic scars.
A Case of Noonan Syndrome and Kyrle Disease: Casualty or Causality?
Acta Dermatovenerol Croat
December 2023
Marco Brusasco, MD, Dermatology Section Department of Medicine and Surgery, University of Parma, Via Gramsci, 14, 43126 Parma, Italy;
Article Synopsis
- A 39-year-old woman with Noonan Syndrome and RAF1 mutation presented with itchy skin lesions on her limbs, which were diagnosed as Kyrle disease (KD) after a detailed examination.
- KD is characterized by dome-shaped papules with a central keratotic plug and is often linked to systemic conditions such as chronic renal failure and diabetes, although this patient did not have these issues.
- Treatment involved narrowband UVB phototherapy, leading to complete resolution of symptoms, which highlights the importance of managing underlying health conditions in skin diseases like KD.
Identifying Human Trafficking Victims: A Potential Role for Forensic Dermatology.
Cureus
November 2023
Dermatology, University of California, Davis Medical Center, Sacramento, USA.
Human trafficking is a worldwide problem that predominantly affects women and children. The victims are recruited by coercion, deception, or force and then exploited for commercial sex acts or labor, or both. Human trafficking results in severe suffering of the victims including not only physical injuries but also psychological consequences.
View Article and Find Full Text PDFA Rare Presentation of Scurvy in a Well-Nourished Patient.
Cureus
October 2023
Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, USA.
Vitamin C deficiency, otherwise known as scurvy, is a rare diagnosis among populations with adequate nutritional resources. We present a 37-year-old female patient with bilateral lower extremity edema, episodic anasarca, petechiae, and easy bruising who was diagnosed with scurvy. Given the clinical presentation, a broad differential was investigated with no findings suggestive of hematologic or cardiovascular pathology.
View Article and Find Full Text PDFand its nano-mediated approach toward management of neurodegenerative disorders: A review.
Ibrain
February 2023
Dr. D. Y. Patil Biotechnology and Bioinformatics Institute, Dr. D. Y. Patil Vidyapeeth Pune Maharashtra India.
L., also known as black seed or black cumin, is a plant that has been used for centuries. In the past, this flowering plant was used as a food preservative and medicinal herb.
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