Purpose: Total package time, or the time from diagnosis to completion of definitive treatment, has been associated with outcomes for a variety of tumor sites, but especially to head and neck (HN) cancer. Patients with HN cancer often undergo a complex diagnosis and treatment process involving multiple disciplines both within and outside of oncology. This complexity can lead to longer package times, and each involved discipline has the responsibility to maintain an efficient and effective process. Strategic intervention to improve package time must involve not only new technology or tools, but also "soft" components such as accountability, motivation, and leadership. This combination is necessary to truly optimize radiation therapy for HN cancer, leading to shorter total package times for these patients.
Methods And Materials: Two interventions were strategically executed to improve radiation therapy workflow: upgrade of the treatment planning system and implementation of an automated patient management and accountability system. The radiation therapy-related timelines of 112 patients with HN cancer treated over 2 years were reviewed, and the average time differences were compared between the patient populations before and after the strategic interventions.
Results: Purely upgrading the treatment planning system did not show significant improvements, but when combined with the patient management system, significant improvement in radiation-related package time can be noted for every time point. The overall reduction of radiation-related package time was statistically significant at 22.85 days ( = .002).
Conclusions: On face value, the patient management system could be credited as responsible for the improvement, but on qualitative analysis, it is noted that the new system is only a tool that can be ignored or underused. Owing to the addition of important "soft" components such as accountability, motivation, and leadership, the patient management system was optimized and implemented in such a manner as to have the desired effect.
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http://dx.doi.org/10.1016/j.adro.2022.101117 | DOI Listing |
Front Child Adolesc Psychiatry
October 2023
DIMAMO Population Health Research Centre, University of Limpopo, Polokwane, South Africa.
Background: Pregnant teenagers have been reported to have an increased likelihood of experiencing depression than their non-pregnant peers. There is little research on the risk factors for depression in rural Black adolescents and young adults, especially after the Covid-19 pandemic. Therefore, the current study aimed to identify the prevalence of probable depression and associated factors amongst pregnant and parenting young females.
View Article and Find Full Text PDFJMIR Hum Factors
January 2025
Department of Cardiovascular Medicine, Fu Jen Catholic University Hospital, New Taipei, Taiwan.
Background: Telemedicine has been utilized in the care of patients with COVID-19, allowing real-time remote monitoring of vital signs. This technology reduces the risk of transmission while providing high-quality care to both self-quarantined patients with mild symptoms and critically ill patients in hospitals.
Objective: This study aims to investigate the application of telemedicine technology in the care of patients with COVID-19, specifically focusing on usability, effectiveness, and patient outcomes in both home isolation and hospital ward settings.
BMC Health Serv Res
January 2025
School of Medicine and Health Management, Huazhong University of Science and Technology, Wuhan, China.
Background: Uncertain times require healthcare entities to demonstrate strong leadership, develop digitalisation, and respond to change in a creative and flexible manner. Based on emerging new institutional theory, we developed and tested a model of how digital transformational leadership (DTL) affects digital intensity (DI) among healthcare entities through the mediating role of organisational agility (OA). In this article, we also examine the moderating role of the country in the studied relationship.
View Article and Find Full Text PDFJ Neurosci
January 2025
Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire 03766, USA.
Microglia respond to cytotoxic protein aggregates associated with the progression of neurodegenerative disease. Pathological protein aggregates activate the microglial NLRP3 inflammasome resulting in proinflammatory signaling, secretion, and potentially pyroptotic cell death. We characterized mixed sex primary mouse microglia exposed to microbial stressors and alpha synuclein preformed fibrils (αsyn PFFs) to identify cellular mechanisms related to Parkinson's disease.
View Article and Find Full Text PDFAnimal
December 2024
Hybu Cig Cymru - Meat Promotion Wales, Ty Rheidol, Parc Merlin, Glan Yr Afon Industrial Estate, Aberystwyth, SY23 3FF, UK.
While many separate research studies have investigated the effect of production and processing factors on eating quality of lamb, the relative impact of these parameters has been difficult to ascertain. In this study, the effect of eighteen production and processing factors on the eating quality of Welsh Lamb was compared, using meat from 624 lambs and assessments by 1920 UK consumers. Four experimental trials provided a balanced assessment of production and processing factors: muscle, breed type, lamb gender, ageing, finishing diet, season, carcase hanging and packaging method.
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