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| http://dx.doi.org/10.3389/fbioe.2022.1070888 | DOI Listing |
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Stem cells in ageing and longevity: a new section in Biogerontology.
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Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
An integrated proteo-transcriptomics approach reveals novel drug targets against multidrug resistant .
Front Microbiol
February 2025
Department of Biophysics, University of Delhi South Campus, New Delhi, India.
Infections due to multidrug-resistant (MDR) are associated with severe morbidity and mortality, worldwide. Microbial drug resistance is a complex phenomenon which is conditioned by an interplay of several genomic, transcriptomic and proteomic factors. Here, we have conducted an integrated transcriptomics and proteomics analysis of MDR to identify genes which are differentially expressed at both mRNA and protein levels.
View Article and Find Full Text PDFViral contamination in cell culture: analyzing the impact of Epstein Barr virus and Ovine Herpesvirus 2.
Front Microbiol
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Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, Lancaster, United Kingdom.
Cell culture techniques are increasingly favored over animal models due to rising costs, time constraints, and ethical concerns regarding animal use. These techniques serve critical roles in disease modeling, drug screening, drug discovery, and toxicity analysis. Notably, cell cultures facilitate primary virus isolation, infectivity assays, biochemical studies, and vaccine production.
View Article and Find Full Text PDF[Dengue fever vaccination Recommendations from the Société Francophone de Médecine Tropicale et de Santé Internationale for Metropolitan France and Overseas Territories].
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Président de la SFMTSI, SFMTSI Société francophone de médecine tropicale et santé internationale (ancienne SPE), Hôpital Pitié-Salpêtrière, Pavillon Laveran, 47-83 Boulevard de l'Hôpital, 75651 Paris cedex 13, France.
Dengue fever is spreading rapidly around the world, affecting nearly half the world's population. Causes include urbanization, human mobility, climate change and the spread of mosquito vectors such as In 2023 and 2024, there was a marked increase in cases and deaths worldwide. In mainland France, the increase in imported cases has generated local transmissions.
View Article and Find Full Text PDFHLA allele and haplotype frequencies of eight Indian populations based on 130,518 registered stem cell donors.
Front Immunol
March 2025
DKMS Group, Tübingen, Germany.
Introduction: In hematopoietic stem cell transplantation, optimal results are achieved when donors and patients are matched regarding their human leukocyte antigen (HLA) genes. Population-specific HLA allele and haplotype frequency distributions determine the probabilities to find matched donors in a stem cell donor registry of given size and ethnic composition.
Methods: To evaluate the needs of Indian patients with regard to future donor recruitment, we analyzed a large data set of =130,518 potential stem cell donors registered with DKMS-BMST, a Bangalore-based donor registry with nationwide donor recruitment activities.
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