A pilot-scale experiment was implemented in a waste bioreactor with an inner capacity of 1 m in order to simulate a real-scale composting process. The waste underwent composting conditions that are typical of the initial bio-oxidation phase, characterised by a high production of volatile organic compounds (VOCs), hydrogen sulphide (HS) and odorants. The waste bioreactor was fed with an intermittent airflow rate of 6 Nm/h. The target of this study was to investigate the air treatment performance of three biofilters with the same size, but filled with different filtering media: (1) wood chips, (2) a two-layer combination of lava rock (50%) and peat (50%), and (3) peat only. The analyses on air samples taken upstream and downstream of the biofilters showed that the combination of lava rock and peat presents the best performance in terms of mean removal efficiency of odour (96%), total VOCs (95%) and HS (77%) concentrations. Wood chips showed the worst abatement performance, with respective mean removal efficiencies of 90%, 88% and 62%. From the results obtained, it is possible to conclude that the combination of lava rock and peat can be considered as a promising choice for air pollution control in waste composting facilities.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1080/09593330.2022.2148570 | DOI Listing |
J Reconstr Microsurg
December 2024
Department of Plastic and Reconstructive Surgery, MedStar Georgetown University Hospital, Washington, District of Columbia.
Background: Multidisciplinary care with vascular surgery and plastic surgery is essential for lower extremity free flap (LEFF) success in the chronic wound population with diabetes and peripheral vascular disease. There is a lack of understanding on performing targeted direct endovascular reperfusion on a vessel that will be used as the flap recipient. Our study compares outcomes of patients who received targeted revascularization (TR) to the recipient vessel for LEFF anastomosis versus nontargeted revascularization (NR) of arterial recipients prior to LEFF.
View Article and Find Full Text PDFClin Genitourin Cancer
December 2024
Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT. Electronic address:
Background: Enfortumab vedotin (EV) is a nectin-4-directed antibody and microtubule inhibitor conjugate indicated for patients with metastatic urothelial carcinoma (mUC) who have received prior platinum-based chemotherapy and PD-1/L1 inhibitors or are ineligible for cisplatin-containing regimens and have undergone at least 1 prior line of therapy. EV is also indicated in combination with pembrolizumab in the first-line setting. However, real-world effectiveness of EV based on treatment line and impact of prior therapy remains unclear.
View Article and Find Full Text PDFHematology Am Soc Hematol Educ Program
December 2024
Department of Hematology/Hematopoietic Cell Transplantation, City of Hope Orange County, Irvine, CA.
Chronic lymphocytic leukemia (CLL) patients who are refractory to both Bruton's tyrosine kinase and B-cell/CLL lymphoma 2 (BCL2) inhibitors face a significant treatment challenge, with limited and short-lasting disease control options. This underscores the urgent need for novel therapeutic strategies. Immunotherapy has emerged as a promising approach to address this unmet need, offering the potential for durable remissions and improved patient outcomes.
View Article and Find Full Text PDFComput Struct Biotechnol J
December 2024
Section of Bioinformatics, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Hammersmith Hospital Campus, Imperial College London, London, W12 0NN, United Kingdom.
Cancer is the second leading cause of disease-related death worldwide, and machine learning-based identification of novel biomarkers is crucial for improving early detection and treatment of various cancers. A key challenge in applying machine learning to high-dimensional data is deriving important features in an interpretable manner to provide meaningful insights into the underlying biological mechanisms We developed a class-based directional feature importance (CLIFI) metric for decision tree methods and demonstrated its use for The Cancer Genome Atlas proteomics data. The CLIFI metric was incorporated into four algorithms, Random Forest (RF), LAtent VAriable Stochastic Ensemble of Trees (LAVASET), and Gradient Boosted Decision Trees (GBDTs), and a new extension incorporating the LAVA step into GBDTs (LAVABOOST).
View Article and Find Full Text PDFRes Sq
November 2024
Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Surgical removal of primary tumors was shown to reverse tumor-mediated immune suppression in pre-clinical models with metastatic disease. However, how cytoreductive surgery in the metastatic setting modulates the immune responses in patients, especially in the context of immune checkpoint therapy (ICT)-containing treatments is not understood. Here, we report the first prospective, non-comparative clinical trial to evaluate the feasibility, clinical benefits, and immunologic changes of combining three different ICT-containing strategies with cytoreductive surgery or biopsy for patients with metastatic clear cell renal cell carcinoma (mccRCC).
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!