Modern literature data are presented on the choice of a drug for hormonal therapy in acute neurosensory hearing loss of various origins, the doses used for systemic therapy, the features and methods of intratympanic administration of glucocorticosteroids, and the evaluation of the effectiveness of treatment with this group of drugs.
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http://dx.doi.org/10.17116/otorino20228705170 | DOI Listing |
Metab Brain Dis
December 2024
Institute of Neurology (Edinger Institute), University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany.
The blood-brain barrier (BBB) is formed by microvascular endothelial cells which are ensembled with pericytes, astrocytes, microglia and neurons in the neurovascular unit (NVU) that is crucial for neuronal function. Given that the NVU and the BBB are highly dynamic and regulated structures, their integrity is continuously challenged by intrinsic and extrinsic factors. Herein, factors from peripheral organs such as gonadal and adrenal hormones may influence vascular function also in CNS endothelial cells in a sex- and age-dependent manner.
View Article and Find Full Text PDFAm J Ophthalmol Case Rep
December 2024
Casey Eye Institute at Oregon Health and Science University, 515 SW Campus Dr., Portland, OR, 97239, USA.
Purpose: Acute idiopathic maculopathy (AIM) is a posterior segment disorder that involves the neurosensory retina, retinal pigment epithelium, and choroidal circulation. When first described, the disease was classified as unilateral, but subsequent reports have found bilateral presentations. There is growing evidence to suggest the coxsackie virus as the etiology, however, other pro-inflammatory conditions have also been temporally linked to fundoscopic findings.
View Article and Find Full Text PDFInt J Mol Sci
October 2024
New York Proton Center, New York, NY 10035, USA.
Rev Peru Med Exp Salud Publica
October 2024
Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú.
We present the case of a young female health worker, resident in a high Andean region of Peru, with recent exposure to farm animals and arthropods, who developed acute febrile undifferentiated syndrome, severe thrombocytopenia and pulmonary and abdominal extravasation. Subsequently, the patient developed meningitis and early onset bilateral neurosensorial hypoacusis and showed reactive serology to acute infection by Rickettsia sp. Epidemiological and clinical considerations in the differential diagnosis for early management are discussed.
View Article and Find Full Text PDFQual Life Res
December 2024
National Centre for Neuroimmunology and Emerging Diseases, Griffith University, 1 Parklands Drive, Southport Gold Coast, Brisbane, QLD, 4222, Australia.
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