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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673087 | PMC |
| http://dx.doi.org/10.1016/j.jinf.2022.11.011 | DOI Listing |
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Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials: Antidepressants for Restricted and Repetitive Behaviors in Autism Spectrum Disorder.
Neuropsychiatr Dis Treat
October 2024
Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Article Synopsis
- Previous randomized controlled trials have largely shown that antidepressants do not provide significant benefits for restricted and repetitive behaviors (RRBs) in individuals with autism spectrum disorder (ASD).
- A systematic review of nine trials involving 609 participants found no notable differences in RRB outcomes between those treated with antidepressants and those given a placebo.
- Only specific antidepressants like clomipramine and fluvoxamine showed some positive effects in small preliminary studies, but these findings need to be verified in larger trials.
Effect of antidepressants on ejaculation dysfunction in patients with depression and anxiety: A systematic review and network meta-analysis.
Andrology
September 2024
Department of Urology, Tianjin Medical University General Hospital, Tianjin, China.
Introduction: Antidepressants may lead to a series of sexual adverse effects (SAEs), among which ejaculation dysfunction (EjD) is often overlooked by clinicians. The purpose of the present network meta-analysis was to assist drug adjustment by comparing and ranking the incidence of EjD among various antidepressants.
Methods: Relevant studies were retrieved from PubMed, Embase, Scopus, Web of Science, ClinicalTrials.
Author Correction: A systematic review and meta-analysis, investigating dose and time of fluvoxamine treatment efficacy for COVID-19 clinical deterioration, death, and Long-COVID complications.
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Natural Products for Neuroprotection and Anti‑Ageing (Neur‑Age Natura) Research Unit, Chulalongkorn University, Bangkok, 10330, Thailand.
Efficacy of Pharmacotherapies for Bulimia Nervosa: A Systematic Review and Meta-Analysis.
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July 2024
Center for Rehabilitation Medicine, Department of Psychiatry, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China (Yu, Shao); The Second Clinical Medical College of Zhejiang, Chinese Medicine University, Hangzhou, Zhejiang, China (Zhang); Hangzhou Xiaoshan No 2 People's Hospital, Hangzhou, Zhejiang, China (Shen).
Objective: The main purpose was to evaluate the efficacy and tolerability of different medications used to treat bulimia nervosa (BN).
Methods: Randomized controlled trials (RCTs) were identified from published sources through searches in PubMed, Cochrane Library, Web of Science, and Embase from inception to November 2022. Primary outcomes were changes in the frequency of binge eating episodes and vomiting episodes from baseline to endpoint.
A systematic review and meta-analysis, investigating dose and time of fluvoxamine treatment efficacy for COVID-19 clinical deterioration, death, and Long-COVID complications.
Sci Rep
June 2024
Natural Products for Neuroprotection and Anti-Ageing (Neur-Age Natura) Research Unit, Chulalongkorn University, Bangkok, 10330, Thailand.
Article Synopsis
- As of January 2024, there have been over 774 million COVID-19 cases and around 7 million deaths, leading to a significant need for treatments that can prevent hospitalization.
- Fluvoxamine, an SSRI, was identified as a potential treatment to reduce clinical deterioration in COVID-19 patients and has been tested in 14 clinical trials, including seven randomized placebo-controlled studies.
- The analysis of these studies indicates that fluvoxamine significantly reduces the risk of clinical deterioration in COVID-19 patients, with a notable lower rate of deterioration in those treated with the drug compared to standard care.
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