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[Multimorbidity in liver surgery].
Chirurgie (Heidelb)
January 2025
Klinik für Allgemein- und Viszeralchirurgie, Universitätsklinikum Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Deutschland.
Multimorbidity is characterized by the presence of at least 3 chronic diseases with a prevalence of more than 50% of patients over 60 years old. The Charlson comorbidity index (CCI) enables a description of the severity of the multimorbidity and also provides a correlation with the postoperative outcome after liver resection. According to this, multimorbid patients are at increased risk of morbidity and mortality after liver resection, mostly due to postoperative liver failure.
View Article and Find Full Text PDF[Research progress of antiviral treatment for patients with chronic hepatitis B combined with metabolic fatty liver disease].
Zhonghua Gan Zang Bing Za Zhi
October 2024
Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan430022, China.
Chronic hepatitis B (CHB) mainly causes cirrhosis and hepatocellular carcinoma (HCC). Metabolic fatty liver disease (MAFLD) has become the most common chronic liver disease worldwide with the continuous changes in lifestyle and dietary patterns and the increase in the number of obese individuals. Consequently, the incidence rate of CHB combined with MAFLD is rapidly increasing.
View Article and Find Full Text PDFLiver at crossroads: unraveling the links between obesity, chronic liver diseases, and the mysterious obesity paradox.
Clin Exp Med
October 2024
Department of Hepatology and Gastroenterology, National Liver Institute, Menoufia University, Shebeen El-Kom, Egypt.
Obesity is a global health issue that is intricately linked to the development and progression of chronic liver disease (CLD). This bidirectional connection, coupled with the obesity paradox (OP), presents a management dilemma. The established influence of obesity on the development and progression of chronic liver disease (CLD) is surpassed by the liver's impact on the onset and advancement of obesity.
View Article and Find Full Text PDFMetabolic-associated fatty liver disease and pregnancy complications: new challenges and clinical perspectives.
Ther Adv Endocrinol Metab
September 2024
Department of Clinical Nutrition, Affiliated Zhongshan Hospital of Dalian University, #6 Jiefang Road, Dalian 116001, China.
The term metabolic-associated fatty liver disease (MAFLD), with a global prevalence estimated at 38.77%, has gradually replaced the traditional concept of non-alcoholic fatty liver disease (NAFLD). Compared to the general population, the incidence of MAFLD is notably higher among pregnant women, posing potential risks to both maternal and neonatal health.
View Article and Find Full Text PDFFatty liver disease - non alcoholic to metabolic - A transition of concepts!!
J Family Med Prim Care
August 2024
Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Wardha, Maharashtra, India.
Article Synopsis
- Metabolic dysfunction associated fatty liver disease (MAFLD) is a new concept defined by experts, highlighting the importance of factors like diabetes, obesity, and metabolic dysregulation alongside the absence of alcohol intake for diagnosis.
- A consensus on MAFLD criteria aims to enhance clinical protocols, improving diagnosis, treatment, and research in liver diseases globally.
- Early recognition of MAFLD is crucial as it significantly increases the risk of serious health issues, making it essential in family medicine and primary care.
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