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One-year epidemiological patterns of respiratory pathogens across age, gender, and seasons in Chengdu during the post-COVID era.
Sci Rep
January 2025
Aba Teachers College, Wenchuan, Scichuan, China.
Respiratory tract infections caused by various pathogens remain a significant public health concern due to their high prevalence and potential for severe complications. This study systematically analyzed the epidemiological characteristics of six common respiratory pathogens-Chlamydia pneumoniae (CP), Mycoplasma pneumoniae (MP), Adenovirus (AdV), Influenza A virus (FluA), Influenza B virus (FluB), and Respiratory Syncytial Virus (RSV)-in patients from Sichuan Jinxin Xinan Women and Children's Hospital between April 2023 and March 2024. Throat swab samples were collected from a total of 22,717 individuals.
View Article and Find Full Text PDFChildhood Respiratory Illnesses Before and After COVID-19 Pandemic Restrictions.
Cureus
November 2024
Pediatric Emergency Medicine, Loma Linda University Medical Center, Loma Linda, USA.
Introduction With the COVID-19 pandemic, multiple studies described a significant drop in common respiratory viruses in children with the lockdown and restrictions. With the lifting of pandemic precautions, we had the ability to observe new patterns of respiratory illnesses in children and emergency department visits. Materials and methods We studied all respiratory nucleic acid amplification test results in emergency patients from a large metropolitan children's hospital from the years 2018 to 2023.
View Article and Find Full Text PDFUpdating the relationship of Chlamydia pneumoniae with atherosclerotic cardiovascular diseases: a systematic review of reviews.
New Microbiol
November 2024
Department of Public Health and Infectious Diseases, University of Rome "Sapienza", Rome, Italy.
Chlamydia pneumoniae is the etiologic agent of respiratory tract infections in humans, including community-acquired pneumonia, and has been associated with atherosclerotic cardiovascular diseases. The present systematic review of reviews aimed at answering important questions on the involvement of C. pneumoniae in the pathogenesis of atherosclerosis, its cellular and molecular mechanisms, and whether there is evidence of a causal relationship.
View Article and Find Full Text PDFERA-CRISPR/Cas12a-based, fast and specific diagnostic detection for .
Front Cell Infect Microbiol
November 2024
The Institute of Pathogenic Biology, Hengyang Medical School, University of South China, Hengyang, China.
Article Synopsis
- This text discusses a new diagnostic system called Cpn-ERA-CRISPR/Cas12a designed to detect a specific intracellular pathogen responsible for respiratory diseases, which is a major public health issue.
- The system combines enzymatic recombination amplification (ERA) with the CRISPR/Cas12a technology, enabling detection via fluorescence and lateral flow methods in as little as 15 to 30 minutes.
- The system demonstrated high specificity by not reacting with other pathogens, achieved 100% detection accuracy in clinical samples, and shows promise for use in community hospitals.
A decision tree for predicting the causative pathogens of community-acquired pneumonia from thin-section computed tomography.
Jpn J Radiol
November 2024
Department of Radiology, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-Machi, Yufu, Oita, 879-5593, Japan.
Purpose: To determine whether decision trees are useful for predicting organisms that cause community-acquired pneumonia (CAP).
Materials And Methods: We developed a decision tree for predicting the organisms that cause CAP based on previously reported characteristic computed tomography findings. Sixteen readers (two student doctors, six residents, and eight radiologists) separately diagnosed 68 randomly selected cases of CAP using chest computed tomography.
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