Evaluation of Cerebellar Ataxic Patients.

Neurol Clin

Initiative for Columbia Ataxia and Tremor, Columbia University, New York, NY, USA; Department of Neurology, Columbia University Irving Medical Center, 650 West 168th Street, Room 305, New York, NY 10032, USA. Electronic address:

Published: February 2023

Cerebellar ataxia results from damage to the cerebellum and presents as movement incoordination and variability, gait impairment, and slurred speech. Patients with cerebellar ataxia can also have cognitive and mood changes. Although the identification of causes for cerebellar ataxia can be complex, age of presentation, chronicity, family history, and associated movement disorders may provide diagnostic clues. There are many genetic causes for cerebellar ataxia, and the common autosomal dominant and recessive ataxia are due to genetic repeat expansions. Step-by-step approach will lead to the identification of the causes. Symptomatic and potential disease-modifying therapies may benefit patients with cerebellar ataxia.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354692PMC
http://dx.doi.org/10.1016/j.ncl.2022.05.002DOI Listing

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