Phages are among the most abundant and diverse biological entities on earth. Phage prediction from sequence data is a crucial first step to understanding their impact on the environment. A variety of bacteriophage prediction tools have been developed over the years. They differ in algorithmic approach, results, and ease of use. We, therefore, developed "What the Phage" (WtP), an easy-to-use and parallel multitool approach for phage prediction combined with an annotation and classification downstream strategy, thus supporting the user's decision-making process by summarizing the results of the different prediction tools in charts and tables. WtP is reproducible and scales to thousands of datasets through a workflow manager (Nextflow). WtP is freely available under a GPL-3.0 license (https://github.com/replikation/What_the_Phage).

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673492PMC
http://dx.doi.org/10.1093/gigascience/giac110DOI Listing

Publication Analysis

Top Keywords

phage prediction
8
prediction tools
8
phage
4
phage scalable
4
scalable workflow
4
workflow identification
4
identification analysis
4
analysis phage
4
phage sequences
4
sequences phages
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!