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The antimicrobial effectiveness of chlorhexidine and chlorhexidine-silver sulfadiazine-impregnated central venous catheters against the emerging fungal pathogen Candida auris.
Am J Infect Control
November 2024
Clinical and Medical Affairs, Vascular and Interventional Divisions, Teleflex Incorporated, Morrisville, NC, USA.
Background: Candida auris is an emerging multidrug-resistant fungus associated with catheter-related bloodstream infections. In vitro efficacy of chlorhexidine (CHX) and CHX-silver sulfadiazine-impregnated (CHX-S) antimicrobial central venous catheters (CVCs) against C auris was investigated.
Methods: Minimum inhibitory and bactericidal CHX concentrations were determined against 19 C auris isolates.
Comparative study of silver-sulfadiazine-impregnated collagen dressing versus conventional burn dressings in second-degree burns.
J Family Med Prim Care
January 2019
Department of Plastic and Reconstructive Surgery, VS General Hospital and NHL Medical College, Ahmedabad, Gujarat, India.
Background: The advantages of biological skin dressings like collagen are well-known. It makes wound impermeable to bacteria and creates the most physiological interface between the wound surface and the environment. Silver-sulfadiazine-impregnated collagen (SIC) is a type 1 collagen impregnated with silver sulfadiazine (SSD)-loaded alginate microspheres to deliver SSD in a controlled fashion to manage infected burn wounds for an extended period of time with lesser dressing changes.
View Article and Find Full Text PDFBackground: Thirteen patients with chlorhexidine-silver sulfadiazine-impregnated catheters have experienced serious anaphylactic shock in Japan. These adverse reactions highlight the lack of commercially available catheters impregnated with strong antibacterial chemical agents. A system should be developed that can control both biocompatibility and antibacterial activity.
View Article and Find Full Text PDFSilver Sulfadiazine-Impregnated Hydrocolloid Dressing Is Beneficial in Split-Thickness Skin-Graft Donor Wound Healing in a Small Randomized Controlled Study.
Int J Low Extrem Wounds
December 2016
1 Nagasaki University, Nagasaki, Japan.
Donor-site wound healing was tested with a silver sulfadiazine (SSD)-impregnated hydrocolloid dressing and hydrocolloid dressing applied manually by a physician on site. A total of 14 patients, 5 woman and 9 men (23-89 years old, average = 61.6 ± 18.
View Article and Find Full Text PDFChlorhexidine-silver sulfadiazine-impregnated venous catheters are efficient even at subclavian sites without tracheostomy.
Am J Infect Control
December 2016
Department of Critical Care, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain.
Background: Chlorhexidine-silver sulfadiazine (CHSS)-impregnated catheters have been found to decrease the risk of catheter-related bloodstream infection (CRBSI) and central venous catheter (CVC)-related costs. However, there are no published data about cost-effectiveness of the use of CHSS-impregnated catheters in subclavian venous access without the presence of tracheostomy (thus, with a very low risk of CRBSI). That was the objective of this study.
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