AI Article Synopsis
- Lymph node recurrence in stage IA1 squamous cell carcinoma (SCC) of the cervix without lymphovascular space invasion (LVSI) is rare, but two cases of extraregional lymph node recurrence were reported after initial surgery.
- Both patients underwent hysterectomy, with recurrence detected through imaging or symptoms, confirming the potential for late recurrence despite initially low-risk diagnoses.
- These cases highlight the need for oncologists to remain vigilant for recurrence even in asymptomatic patients, suggesting serum SCC antigen testing as a valuable tool for early detection.
Article Abstract
Lymph node recurrence is extremely rare in cases of stage IA1 squamous cell carcinoma (SCC) of the uterine cervix without lymphovascular space invasion (LVSI). We present two cases of extraregional lymph node recurrence after initial surgery for stage IA1 SCC of the uterine cervix without LVSI. Both patients initially underwent hysterectomy and developed recurrent extraregional lymph nodes within a few years postoperatively. Case 1: The patient showed no symptoms of recurrence, and follow-up computed tomography (CT) for evaluation of gallstones revealed a para-aortic lymph node (9 mm). The patient subsequently underwent serum SCC antigen testing and CT and was diagnosed with recurrence. Case 2: The patient noticed a right inguinal node swelling, which was evaluated using CT. Both patients survived without relapse for 8 and 4 years, respectively. Although stage IA1 SCC of the uterine cervix without LVSI is associated with a low risk of lymph node recurrence, oncologists should consider the possibility of recurrence in such cases. Evaluation for recurrence is difficult in asymptomatic patients. Serum SCC antigen testing may be a useful biochemical marker before imaging for early detection of recurrence, even in asymptomatic patients.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613371 | PMC |
| http://dx.doi.org/10.2185/jrm.2022-010 | DOI Listing |
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