Our objective was to map and prioritize barriers to high-quality family planning care in western Kenya. We conducted key informant interviews ( = 19); focus group discussions with clients ( = 55); mystery client visits ( = 180); unannounced visitors ( = 120); and direct observation of client-provider interactions ( = 256) at public facilities offering family planning. We synthesized the data into a client and a provider journey map, which we used to facilitate client ( = 9) and provider ( = 12) discussions. For both groups, stockouts were frequent, impactful, and important barriers. Clients also reported male partner resistance, insufficient counseling, and informal fees were priority barriers.
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http://dx.doi.org/10.1080/07399332.2022.2135097 | DOI Listing |
Qual Life Res
December 2024
Akdeniz University Hospital, Antalya, 07070, Türkiye.
Background: Despite advances in transplant procedures, children and adolescents still face some challenges post-transplant and are at high risk for psychiatric, academic, and social problems. This study aims to explore the lived experiences of adolescent kidney transplant recipients through interviews and the use of mandala art therapy.
Methods: This study adopted a descriptive phenomenological design and thematic analysis approach based on Husserl's philosophy.
Adv Healthc Mater
December 2024
School of Medicine, 411 Hospital of Shanghai University, Shanghai University, Shanghai, 200444, China.
Hepatic diseases cause serious public health problems worldwide, and there is an urgent need to develop effective therapeutic agents. In recent years, significant progress is made in RNA therapy, and RNA molecules, such as mRNAs, siRNAs, miRNAs, and RNA aptamers, are shown to provide significant advantages in the treatment of hepatic diseases. However, the drawbacks of RNAs, such as their poor biological stability, easy degradation by nucleases in vivo, low bioavailability, and low concentrations in target tissues, significantly limit the clinical application of RNA-based drugs.
View Article and Find Full Text PDFCureus
November 2024
Department of Community Medicine, Al-Rayan National College of Medicine, Madinah, SAU.
Shenxian-Shengmai (SXSM) is a Chinese patent medicine used in the treatment of sick sinus syndrome (SSS). However, its active chemical compounds and the underlying molecular mechanisms remain unclear. In this study, we researched the underlying mechanisms of SXSM in treating SSS.
View Article and Find Full Text PDFEnviron Health (Wash)
December 2024
Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
The adverse effect of ambient PM exposure on very early pregnancy (VEP) remains controversial among epidemiological studies but is supported by toxicological evidence. We adopted a multicenter retrospective cohort of 141,040 cycles to evaluate the effect of PM exposure on the VEP using the fertilization and embryo transfer platform and high-resolution PM data in China. We first investigated the association between PM exposure 1 week before and 1 week after the embryo transfer date and VEP.
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