Spinal epidural metastasis from cervical cancer: Report of two cases and literature review.

Gynecol Oncol Rep

Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, People's Republic of China.

Published: December 2022

Spinal epidural metastasis(SEM) from cervical cancer is extremely rare, with only 6 cases reported in the literature, including our reported 2 cases. SEM mostly occurs in poorly differentiated carcinoma. Hematogenous spread is the primary mechanism of SEM from cervical cancer. The patients with SEM usually present with a range of clinical manifestations of nervous system because of spinal cord compression. SEM from cervical cancer indicates a late event with a poor prognosis. Local treatments mainly include surgery decompression and radiotherapy. Combining local and systemic therapy might be a better choice to prolong survival.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643406PMC
http://dx.doi.org/10.1016/j.gore.2022.101096DOI Listing

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