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Bioprocess development for microbial production and purification of cellobiose lipids by the smut fungus Ustilago maydis DSM 4500.
Bioprocess Biosyst Eng
January 2025
Department of Chemical Engineering, Stellenbosch University, Private Bag X1, Matieland, 7602, South Africa.
Cellobiose lipids (CBLs) are a class of glycolipid biosurfactants produced by various fungal strains. These compounds have gained significant interest due to their surface-active and antifungal properties, which are comparable to traditional synthetic surfactants and antimicrobials. Despite their potential applicability in various cosmetic, pharmaceutical, and agricultural formulations, significantly less research has been focused on their production and purification in comparison to other glycolipid biosurfactants, such as mannosylerythritol lipids (MELs) and sophorolipids.
View Article and Find Full Text PDFComparison of Maximum Isometric Strength of the Hip Joint Abductor and Knee Joint Extensor Muscles between Knee Osteoarthritis Patients with and without Self-reported Instability.
Z Orthop Unfall
January 2025
Institute of Cardiology and Sports Medicine, Department II: Molecular and Cellular Sports Medicine, German Sport University Cologne, Cologne, Germany.
Patients with knee osteoarthritis (KOA) often have impaired muscle function of the weight-bearing muscles, particularly in the knee and hip joints. This can lead to a significant loss of strength and power and may play a role in the perceived instability of the knee joint. The purpose of this study was to compare the maximum isometric strength of the hip abductor and knee extensor muscles between patients with KOA with and without perceived instability.
View Article and Find Full Text PDF[Rapid Assessment of Future Pandemic Effects in Individuals with Severe Mental Illness: Can Ongoing Population-Representative Cohorts Contribute?].
Psychiatr Prax
January 2025
Institut für Sozialmedizin, Arbeitsmedizin und Public Health (ISAP), Universität Leipzig Medizinische Fakultät, Leipzig.
To provide an overview of ongoing cohorts including severely mentally ill patients to study collateral effects of pandemics.Systematic literature search.None of the ongoing German health cohorts includes people with severe mental illness (SMI).
View Article and Find Full Text PDFExploring the Mechanism for Increased Risk in Freeway Tunnel Approach Zones: A Perspective on Temporal-spatial Evolution of Driving Predictions, Tasks, and Behaviors.
Accid Anal Prev
January 2025
School of Transportation and Logistics Engineering, Wuhan University of Technology, Wuhan 430063, PR China.
Freeway tunnel approach zones, situated outside the tunnel, do not undergo the same sudden changes in luminous environment and visual references that entrance zones experience. Despite this, accident data indicates that approach zones present similar safety risks to entrance zones, both of which are significantly higher than other tunnel sections. The reasons for the heightened risks in approach zones remain unclear in existing research.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Xiangya Hospital, Central South University, Changsha, Hunan, China.
Background: Existing biomarkers including cerebrospinal fluid and positron emission tomography for Alzheimer's disease (AD) diagnosis are relatively invasive and expensive. Application of exhaled breath collection and volatile organic compound (VOC) detection for AD diagnosis remains unclear.
Method: In this cross-sectional study, high-pressure photon ionization time-of-flight mass spectrometry (HPPI-ToF-MS) was used to detect VOCs from breath in three datasets and patients diagnosed as Parkinson's disease (PD).
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