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Exploring Traditional Medicine Diagnostic Classification for Parkinson's Disease Using Hierarchical Clustering.
Complement Med Res
February 2024
KM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.
Introduction: Personalized diagnosis and therapy for Parkinson's disease (PD) are needed due to the clinical heterogeneity of PD. Syndrome differentiation (SD) in traditional medicine (TM) is a diagnostic method for customized therapy that comprehensively analyzes various symptoms and systemic syndromes. However, research identifying PD classification based on SD is limited.
View Article and Find Full Text PDFPersonalisierte Behandlung des Gorlin-Goltz-Syndroms: Erfahrungen mit der Kombinationstherapie und unser Algorithmus für die Behandlung.
J Dtsch Dermatol Ges
November 2022
Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
[Immunotherapy and personalized treatment of multiple sclerosis].
Nervenarzt
October 2021
Neurologische Klinik, St. Josef-Hospital, Ruhr-Universität-Bochum, Bochum, Deutschland.
Personalized medicine requires a patient-oriented approach with the exact classification of the disease being determined by the underlying pathophysiological processes. In particular, the optimal treatment of multiple sclerosis (MS) requires personalized treatment that goes beyond the pure concept of precision medicine; however, due to the lack of robust biomarkers beyond cranial magnetic resonance imaging and a lacking detailed understanding of some aspects of MS pathogenesis, this approach is not yet fully implemented. Important questions for a better therapeutic stratification of MS patients are: (1) when does MS start? (2) Does the spectrum of MS really span multiple diseases? (3) When does the progressive phase of the disease begin? (4) In which phase of the disease is there a therapeutic window for immunotherapy? Recent findings indicate that MS represents a spectrum of diseases and that there is a therapeutic delay of several years, on which the optimal treatment effect of a disease-modifying treatment depends.
View Article and Find Full Text PDF[Digital forms of service delivery for personalized crisis resolution and home treatment].
Nervenarzt
March 2022
Abteilung Public Mental Health, Zentralinstitut für Seelische Gesundheit, Medizinische Fakultät Mannheim, Universität Heidelberg, J5, 68159, Mannheim, Deutschland.
Background: Ward-equivalent treatment (StäB), a form of crisis resolution and home treatment in Germany, has been introduced in 2018 as a new model of mental health service delivery for people with an indication for inpatient care. The rapid progress in the field of information and communication technology offers entirely new opportunities for innovative digital mental health care, such as telemedicine, eHealth, or mHealth interventions.
Objective: This review aims to provide a comprehensive overview of novel digital forms of service delivery that may contribute to a personalized delivery of StäB and improving clinical and social outcomes as well as reducing direct and indirect costs.
[Personalized medicine in the treatment of eye tumors : Connection between molecular biology, clinical aspects and personal needs of patients].
Ophthalmologe
June 2020
Klinik für Augenheilkunde, Universitätsklinikum Schleswig-Holstein, Campus Lübeck Universität zu Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.
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