A simple method is proposed in this work for the detection of SARS-CoV-2 RNA based on a functional RNA/DNA circuit. By ingeniously integrating the nucleic acid circuit technology and CRISPR/cas12a system, this method can achieve femtomolar detection of the target RNA in one step and successfully distinguish COVID-19 positive cases from clinical samples, proving its great potential for clinical application.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d2cc05251b | DOI Listing |
Publication Analysis
Top Keywords
functional rna/dna
8
rna/dna circuit
8
detection sars-cov-2
8
sars-cov-2 rna
8
circuit one-pot
4
one-pot detection
4
rna simple
4
simple method
4
method proposed
4
proposed work
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!