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Should we adopt a prognosis-based approach to unexplained infertility? | LitMetric

Should we adopt a prognosis-based approach to unexplained infertility?

Hum Reprod Open

Medical Statistics Team, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UK.

Published: October 2022

AI Article Synopsis

Article Abstract

The treatment of unexplained infertility is a contentious topic that continues to attract a great deal of interest amongst clinicians, patients and policy makers. The inability to identify an underlying pathology makes it difficult to devise effective treatments for this condition. Couples with unexplained infertility can conceive on their own and any proposed intervention needs to offer a better chance of having a baby. Over the years, several prognostic and prediction models based on routinely collected clinical data have been developed, but these are not widely used by clinicians and patients. In this opinion paper, we propose a prognosis-based approach such that a decision to access treatment is based on the estimated chances of natural and treatment-related conception, which, in the same couple, can change over time. This approach avoids treating all couples as a homogeneous group and minimizes unnecessary treatment whilst ensuring access to those who need it early.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662706PMC
http://dx.doi.org/10.1093/hropen/hoac046DOI Listing

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