AI Article Synopsis

  • Methotrexate (MTX) has been used for over 50 years in low doses to treat psoriasis due to its immunosuppressive and anti-inflammatory effects.
  • Some potential side effects of MTX include pancytopenia, liver issues, respiratory toxicity, and acute renal failure.
  • This case study focuses on a patient who experienced severe symptoms of MTX toxicity due to an accidental overdose while being treated for psoriasis.

Article Abstract

For more than 50 years, methotrexate (MTX), when used in low doses, has been one of the most commonly used drugs in the treatment of psoriasis. It has immunosuppressive as well as anti-inflammatory properties. Pancytopenia, hepatic dysfunction, respiratory toxicity, and acute renal failure are some of the reported side effects. This is a case study of a patient who had developed florid symptoms of methotrexate toxicity as a result of erroneous overdosing of methotrexate, which was given to her for psoriasis management.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637408PMC
http://dx.doi.org/10.7759/cureus.30041DOI Listing

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